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Zhang Q, Lv XY, Yang YM. Megaloblastic anemia with hypotension and transient delirium as the primary symptoms: report of a case. Int J Clin Exp Med. 2015;8(10):18879-83
Zhang, Q., Lv, X. Y., & Yang, Y. M. (2015). Megaloblastic anemia with hypotension and transient delirium as the primary symptoms: report of a case. International journal of clinical and experimental medicine, 8(10), 18879-83.
Zhang, Qin, et al. "Megaloblastic anemia with hypotension and transient delirium as the primary symptoms: report of a case." International journal of clinical and experimental medicine vol. 8,10 (2015): 18879-83.
Zhang Q, Lv XY, Yang YM. Megaloblastic anemia with hypotension and transient delirium as the primary symptoms: report of a case. Int J Clin Exp Med. 2015 Oct 15;8(10):18879-83. eCollection 2015. PMID: 26770511; PMCID: PMC4694411.
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Int J Clin Exp Med. 2015 Oct 15;8(10):18879-83. eCollection 2015.

Megaloblastic anemia with hypotension and transient delirium as the primary symptoms: report of a case.

International journal of clinical and experimental medicine

Qin Zhang, Xue-Ying Lv, Yun-Mei Yang

Affiliations

  1. Department of Geriatrics, The First Affiliated Hospital, School of Medicine, Zhejiang University Hangzhou, China.

PMID: 26770511 PMCID: PMC4694411

Abstract

The present study describes a case of an elderly patient that was hospitalized secondary to hypotension and delirium. Physical examination at admission revealed bilateral positive Babinski's sign. Laboratory examination revealed severe anemia. Bone marrow examination showed megaloblastic changes of the granulocyte and erythroid series, as well as other dyshaematopoiesis. The conditions of the patient rapidly improved after vitamin B12 treatments. Because the clinical manifestations of megaloblastic anemia are complex, this disease is often misdiagnosed in the geriatric population. Bone marrow examinations can aid in the diagnosis of anemia, but the results from these tests cannot always differentiate the type of anemia. Clinical management of the disorder is reliant upon proper classification of the type of anemia. The prognosis of megaloblastic anemia is typically good and a simple regimen of folic acid and/or vitamin B12 is effective.

Keywords: Megaloblastic anemia; delirium; elderly; hypotension; vitamin B12

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