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Liao PJ, Xie RB, Yin RX, et al. Serum lipid profiles, the prevalence of dyslipidemia and the risk factors in two isolated Chinese minorities. Int J Clin Exp Med. 2015;8(10):19200-11
Liao, P. J., Xie, R. B., Yin, R. X., Wei, D. X., Huang, J., Huang, F., Li, H., Lin, W. X., Wu, J. Z., & Pan, S. L. (2015). Serum lipid profiles, the prevalence of dyslipidemia and the risk factors in two isolated Chinese minorities. International journal of clinical and experimental medicine, 8(10), 19200-11.
Liao, Pei-Juan, et al. "Serum lipid profiles, the prevalence of dyslipidemia and the risk factors in two isolated Chinese minorities." International journal of clinical and experimental medicine vol. 8,10 (2015): 19200-11.
Liao PJ, Xie RB, Yin RX, Wei DX, Huang J, Huang F, Li H, Lin WX, Wu JZ, Pan SL. Serum lipid profiles, the prevalence of dyslipidemia and the risk factors in two isolated Chinese minorities. Int J Clin Exp Med. 2015 Oct 15;8(10):19200-11. eCollection 2015. PMID: 26770556; PMCID: PMC4694456.
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Int J Clin Exp Med. 2015 Oct 15;8(10):19200-11. eCollection 2015.

Serum lipid profiles, the prevalence of dyslipidemia and the risk factors in two isolated Chinese minorities.

International journal of clinical and experimental medicine

Pei-Juan Liao, Rui-Bin Xie, Rui-Xing Yin, Dai-Xun Wei, Jian Huang, Feng Huang, Hui Li, Wei-Xiong Lin, Jin-Zhen Wu, Shang-Ling Pan

Affiliations

  1. Department of Cardiology, Institute of Cardiovascular Diseases, The First Affiliated Hospital, Guangxi Medical University Nanning, China.
  2. Department of Cardiology, Hezhou People's Hospital Hezhou, China.
  3. The Disease Control and Prevention Center Luocheng Mulao Autonomous County, Hechi, China.
  4. Department of General Practice, Jiangping Health Station of Dongxing City Dongxing, China.
  5. Clinical Laboratory of The Affiliated Cancer Hospital, Guangxi Medical University Nanning, China.
  6. Department of Molecular Genetics, Medical Scientific Research Center, Guangxi Medical University Nanning, China.
  7. Department of Pathophysiology, School of Premedical Sciences, Guangxi Medical University Nanning, China.

PMID: 26770556 PMCID: PMC4694456

Abstract

Both Jing and Mulao nationalities are the isolated minorities in China. Little is known about the prevalence of dyslipidemia between the two ethnic groups. Therefore, the aim of this study was to compare the differences in serum lipid profiles, the prevalence of dyslipidemia and their risk factors between the Jing and Mulao populations. A cross-sectional study of dyslipidemia was conducted in Dongxing city, Guangxi, China, during Dec 2011 and Jan 2012. A total of 1254 subjects of Jing and 1251 participants of Mulao were surveyed by a stratified randomized sampling. Information on demography, diet and lifestyle was collected with standardized questionnaire. Serum lipid levels were detected using the commercially available kits. The levels of low-density lipoprotein cholesterol (LDL-C), apolipoprotein (Apo) A1, and the ratio of ApoA1 to ApoB were lower but the levels of ApoB were higher in Jing than in Mulao (P < 0.001 for all). The prevalence of hypertriglyceridemia (32.38% vs. 24.38%), high ApoB (35.25% vs. 15.35%) and low ApoA1/ApoB ratio (22.65% vs. 16.87%) was higher and low high-density lipoprotein cholesterol (0.48% vs. 2.16%), high LDL-C (17.54% vs. 40.53%) and low ApoA1 (5.98% vs. 11.43%) was lower in Jing than in Mulao (P < 0.001 for all). The risk factors for serum lipid parameters and hyperlipidemia were different between the two ethnic groups. Serum lipid profiles, the prevalence of dyslipidemia and their risk factors are different between the Jing and Mulao populations. These differences may result from the combined effects of different diet, lifestyle, and genetic factors.

Keywords: Lipids; apolipoproteins; dyslipidemia; prevalence; risk factors

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