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Case Rep Oncol Med. 2015;2015:941508. doi: 10.1155/2015/941508. Epub 2015 Dec 03.

An Unusual Course of Metastatic Gastroesophageal Cancer.

Case reports in oncological medicine

William H Smith, Sofya Pintova, Christopher J DiMaio, Panagiotis Manolas, Dong-Seok Lee, Spiros P Hiotis, Maria Kartsonis, Randall F Holcombe, Kavita V Dharmarajan

Affiliations

  1. Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  2. Department of Medical Oncology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY 10029, USA.
  3. Department of Gastroenterology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY 10029, USA.
  4. Department of Surgery, Icahn School of Medicine at Mount Sinai Hospital, New York, NY 10029, USA.
  5. Department of Thoracic Surgery, Icahn School of Medicine at Mount Sinai Hospital, New York, NY 10029, USA.
  6. Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY 10029, USA.

PMID: 26770853 PMCID: PMC4681789 DOI: 10.1155/2015/941508

Abstract

We are reporting on a case of a 41-year-old woman who presented with metastatic gastroesophageal junction cancer and who achieved prolonged survival with a multimodal treatment approach. After initially experiencing robust response to chemotherapy, she was treated for distant recurrence with palliative radiation to the gastrohepatic and supraclavicular lymph nodes and subsequently, given her unusual near-complete response, with reirradiation to the abdomen with curative intent for residual disease. The case presented is unique due to the patient's atypical treatment course, including technically difficult reirradiation to the abdomen, and the resulting prolonged survival despite metastatic presentation.

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