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Castelein S, Liemburg EJ, de Lange JS, et al. Daling suïcidecijfer na eerste psychose: een vergelijking met de situatie van twee decennia terug. [Drop in suicide rate after first psychosis: a comparison with the situation two decades ago]. Ned Tijdschr Geneeskd. 2015;159:A9565
Castelein, S., Liemburg, E. J., de Lange, J. S., van Es, F., Visser, E., Aleman, A., Bruggemans, R., & Knegtering, H. (2015). Daling suïcidecijfer na eerste psychose: een vergelijking met de situatie van twee decennia terug. [Drop in suicide rate after first psychosis: a comparison with the situation two decades ago]. Nederlands tijdschrift voor geneeskunde, 159A9565.
Castelein, Stynke, et al. "Daling suïcidecijfer na eerste psychose: een vergelijking met de situatie van twee decennia terug." [Drop in suicide rate after first psychosis: a comparison with the situation two decades ago]. Nederlands tijdschrift voor geneeskunde vol. 159 (2015): A9565.
Castelein S, Liemburg EJ, de Lange JS, van Es F, Visser E, Aleman A, Bruggemans R, Knegtering H. Daling suïcidecijfer na eerste psychose: een vergelijking met de situatie van twee decennia terug. [Drop in suicide rate after first psychosis: a comparison with the situation two decades ago]. Ned Tijdschr Geneeskd. 2015;159:A9565. Dutch. PMID: 26732214.
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Ned Tijdschr Geneeskd. 2015;159:A9565.

[Drop in suicide rate after first psychosis: a comparison with the situation two decades ago].

Nederlands tijdschrift voor geneeskunde

[Article in Dutch]
Stynke Castelein, Edith J Liemburg, Jill S de Lange, Frank D van Es, Ellen Visser, André Aleman, Richard Bruggemans, Henderikus Knegtering

Affiliations

  1. *Dit onderzoek werd eerder gepubliceerd in PLoS One (2015;10:e0129263) met als titel 'Suicide in recent onset psychosis revisited: significant reduction of suicide rate over the last two decades - a replication study of a Dutch incidence cohort'. Afgedrukt met toestemming.

PMID: 26732214

Abstract

OBJECTIVE: Over two decades ago a study reported that a percentage as high as 11% of the patients with a psychotic disorder in the northern Netherlands died by committing suicide. The primary objective of the current study was to replicate these findings in the same geographical area. A secondary objective was to investigate potential predictors of suicide.

DESIGN: Retrospective cohort study.

METHOD: From patient files we identified the current status of all patients who experienced their first episode of psychosis and participated in the Psychosis Recent Onset Groningen-Survey (PROGR-S) between 2000 and 2009. The PROGR-S is a diagnostic protocol for persons with suspected first psychosis. Kaplan-Meier survival analysis was used to identify the current suicide risk in this group and this was compared with the 1973-1988 patients using a log rank test. We also determined the standardized mortality rate in relation to the general population. Cox regression analysis was used to assess significant predictors of suicide.

RESULTS: The suicide risk dropped drastically over the course of two decades from 11% to 2.4%. Older age was the strongest predictor of suicide. The standardized mortality rate was 41.6.

CONCLUSION: Despite the significant decline in suicide after a first episode of psychosis, the risk of suicide should be given the highest priority in psychiatric psychosis care, as it is very high at 4162% compared with the suicide risk in general population.

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