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Surg Pathol Clin. 2011 Jun;4(2):625-50. doi: 10.1016/j.path.2011.03.004. Epub 2011 May 30.

Pancreatitis, Other Inflammatory Lesions, and Pancreatic Pseudotumors.

Surgical pathology clinics

Alton B Farris, Olca Basturk, N Volkan Adsay

Affiliations

  1. Department of Pathology and Laboratory Medicine, Emory University Hospital, Emory University, 1364 Clifton Road Northeast, Room H-188, Atlanta, GA 30322, USA. Electronic address: [email protected].
  2. Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  3. Department of Pathology and Laboratory Medicine, Emory University, 1364 Clifton Road NE, Room H-180B, Atlanta, GA 30322, USA.

PMID: 26837491 DOI: 10.1016/j.path.2011.03.004

Abstract

The pancreas is versatile in the diversity of disorders that it can exhibit. In this article, characteristics of disorders such as chronic, autoimmune, eosinophilic, hereditary, and infectious pancreatitis are described. With regard to autoimmune pancreatitis, the role of clinical evaluation, histologic examination, and IgG4 immunohistochemistry is discussed. The role of pancreatitis in the pathogenesis of diabetes is also mentioned. Some implications of pancreatitis are highlighted, including the neoplastic predisposition caused by inflammatory lesions of the pancreas. The goal of this article is to convey an appreciation of these disorders because their recognition can benefit patients tremendously, as inflammatory lesions of the pancreas can be mass-forming, giving rise to pseudotumors, and leading to surgical resection that may otherwise be unnecessary.

Copyright © 2011 Elsevier Inc. All rights reserved.

Keywords: Autoimmune; Diabetes; Inflammatory lesions; Pancreas; Pancreatitis; Pathology; Pseudotumors

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