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Pediatr Int. 2016 Jun;58(6):493-496. doi: 10.1111/ped.12835. Epub 2016 Feb 03.

Eosinophilic enteritis due to cow's milk allergy: Possible cause of anastomosis failure following repair of focal intestinal perforation.

Pediatrics international : official journal of the Japan Pediatric Society

Satoshi Yokoyama, Akinori Sekioka, Hirofumi Utsunomiya, Koji Yokoyama, Yuka Ikeda, Shigeto Hara, Akira Yoshida

Affiliations

  1. Department of Pediatric Surgery, Japanese Red Cross Society, Wakayama Medical Center, Wakayama, Japan.
  2. Department of Pediatrics, Japanese Red Cross Society, Wakayama Medical Center, Wakayama, Japan.

PMID: 26841092 DOI: 10.1111/ped.12835

Abstract

Reports of cow's milk allergy (CMA) after neonatal gastrointestinal surgery have recently increased. In recent years it has been suggested that the development of CMA after gastrointestinal surgery in newborn infants is due to an immune function. In addition, the development of CMA might be synergistically exacerbated by congenital abnormalities of the intestinal mucosa, general conditional changes and local damage to the intestine by invasive surgery, and poor pre- or post-surgical nutrition. CMA manifests as a variety of symptoms, such as mild vomiting and bloody stool, decreased activity, poor oral intake, and ileus. CMA may also rarely cause gastrointestinal perforation. Here, we report the case of a newborn infant who developed CMA following repair of focal small intestinal perforation, in which eosinophilic enteritis was suspected to be a possible cause of anastomosis leakage.

© 2016 Japan Pediatric Society.

Keywords: allergen-specific lymphocyte stimulation test; anastomosis leakage; cow's milk allergy; eosinophilic enteritis

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