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Boukhris M, Tomasello SD, Galassi AR. Fatal derecruitment of occluded left anterior descending collaterals after left circumflex revascularization. J Saudi Heart Assoc. 2015;28(1):52-8doi: 10.1016/j.jsha.2015.09.001.
Boukhris, M., Tomasello, S. D., & Galassi, A. R. (2016). Fatal derecruitment of occluded left anterior descending collaterals after left circumflex revascularization. Journal of the Saudi Heart Association, 28(1), 52-8. https://doi.org/10.1016/j.jsha.2015.09.001
Boukhris, Marouane, et al. "Fatal derecruitment of occluded left anterior descending collaterals after left circumflex revascularization." Journal of the Saudi Heart Association vol. 28,1 (2016): 52-8. doi: https://doi.org/10.1016/j.jsha.2015.09.001
Boukhris M, Tomasello SD, Galassi AR. Fatal derecruitment of occluded left anterior descending collaterals after left circumflex revascularization. J Saudi Heart Assoc. 2016 Jan;28(1):52-8. doi: 10.1016/j.jsha.2015.09.001. Epub 2015 Sep 11. PMID: 26778906; PMCID: PMC4685240.
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J Saudi Heart Assoc. 2016 Jan;28(1):52-8. doi: 10.1016/j.jsha.2015.09.001. Epub 2015 Sep 11.

Fatal derecruitment of occluded left anterior descending collaterals after left circumflex revascularization.

Journal of the Saudi Heart Association

Marouane Boukhris, Salvatore D Tomasello, Alfredo R Galassi

Affiliations

  1. Catheterization Laboratory and Cardiovascular Interventional Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy; Faculty of Medicine of Tunis, University Tunis El Manar, Tunis, Tunisia.
  2. Catheterization Laboratory and Cardiovascular Interventional Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

PMID: 26778906 PMCID: PMC4685240 DOI: 10.1016/j.jsha.2015.09.001

Abstract

Coronary arteries are not definitely functionally terminal arteries, as previously thought; indeed, they are linked and interconnected by a rich network of collaterals. Chronic total occlusions (CTOs) represent a subset of frequent lesions encountered in everyday catheterization laboratory practice, generally associated with a developed system of collateral connections. These latter have the capacity to prevent myocardial necrosis and may even uphold metabolic supply to the ischemic territory to maintain its contractile capacity. Authors have reported a rapid and progressive reduction of collateral function and their decline after antegrade flow restoration, resulting in higher myocardial susceptibility to ischemia in the CTO territory. Here, we report the case of a fatal derecruitment of collaterals for a left anterior descending CTO not reopened, after left circumflex subocclusion revascularization.

Keywords: Chronic total occlusion; Collateral circulation; Collateral derecruitment

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