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Schwartz SG, Grzybowski A, Flynn HW. Antibiotic prophylaxis: different practice patterns within and outside the United States. Clin Ophthalmol. 2016;10:251-6doi: 10.2147/OPTH.S100429.
Schwartz, S. G., Grzybowski, A., & Flynn, H. W. (2016). Antibiotic prophylaxis: different practice patterns within and outside the United States. Clinical ophthalmology (Auckland, N.Z.), 10251-6. https://doi.org/10.2147/OPTH.S100429
Schwartz, Stephen G, et al. "Antibiotic prophylaxis: different practice patterns within and outside the United States." Clinical ophthalmology (Auckland, N.Z.) vol. 10 (2016): 251-6. doi: https://doi.org/10.2147/OPTH.S100429
Schwartz SG, Grzybowski A, Flynn HW. Antibiotic prophylaxis: different practice patterns within and outside the United States. Clin Ophthalmol. 2016 Jan 28;10:251-6. doi: 10.2147/OPTH.S100429. eCollection 2016. PMID: 26869761; PMCID: PMC4734782.
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Clin Ophthalmol. 2016 Jan 28;10:251-6. doi: 10.2147/OPTH.S100429. eCollection 2016.

Antibiotic prophylaxis: different practice patterns within and outside the United States.

Clinical ophthalmology (Auckland, N.Z.)

Stephen G Schwartz, Andrzej Grzybowski, Harry W Flynn

Affiliations

  1. Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
  2. Department of Ophthalmology, Poznan City Hospital, Poznan, Poland.

PMID: 26869761 PMCID: PMC4734782 DOI: 10.2147/OPTH.S100429

Abstract

Endophthalmitis remains a rare but important cause of visual loss. Prophylaxis strategies are important to reduce rates of endophthalmitis after cataract surgery, intravitreal injection, and other procedures. There is substantial variability between the US and the rest of the world. During cataract surgery, intracameral antibiotics are commonly used in many nations, especially in Europe, but are less commonly used in the US. A randomized clinical trial from the European Society of Cataract and Refractive Surgeons reported an approximately fivefold reduction in endophthalmitis rates associated with intracameral cefuroxime but these results are controversial. There are no randomized clinical trials regarding endophthalmitis associated with intravitreal injection. Topical antibiotics are commonly used in many nations, but are less commonly used in the US. At this time, there is no global consensus and it appears unlikely that additional major clinical trials will conclusively define the optimal endophthalmitis prophylaxis techniques.

Keywords: cataract surgery; endophthalmitis; intracameral antibiotic; intravitreal injection; prophylaxis

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