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Kawai H, Matsushita H, Ohmachi K, et al. Four hepatosplenic T-cell lymphoma cases of Japanese patients. Leuk Res Rep. 2015;5:3-6doi: 10.1016/j.lrr.2015.12.001.
Kawai, H., Matsushita, H., Ohmachi, K., Kojima, M., Machida, S., Ogawa, Y., Kawada, H., Nakamura, N., & Ando, K. (2016). Four hepatosplenic T-cell lymphoma cases of Japanese patients. Leukemia research reports, 53-6. https://doi.org/10.1016/j.lrr.2015.12.001
Kawai, Hidetsugu, et al. "Four hepatosplenic T-cell lymphoma cases of Japanese patients." Leukemia research reports vol. 5 (2016): 3-6. doi: https://doi.org/10.1016/j.lrr.2015.12.001
Kawai H, Matsushita H, Ohmachi K, Kojima M, Machida S, Ogawa Y, Kawada H, Nakamura N, Ando K. Four hepatosplenic T-cell lymphoma cases of Japanese patients. Leuk Res Rep. 2015 Dec 15;5:3-6. doi: 10.1016/j.lrr.2015.12.001. eCollection 2016. PMID: 26870659; PMCID: PMC4711307.
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Leuk Res Rep. 2015 Dec 15;5:3-6. doi: 10.1016/j.lrr.2015.12.001. eCollection 2016.

Four hepatosplenic T-cell lymphoma cases of Japanese patients.

Leukemia research reports

Hidetsugu Kawai, Hiromichi Matsushita, Ken Ohmachi, Minoru Kojima, Shinichiro Machida, Yoshiaki Ogawa, Hiroshi Kawada, Naoya Nakamura, Kiyoshi Ando

Affiliations

  1. Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
  2. Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
  3. Department of Pathology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.

PMID: 26870659 PMCID: PMC4711307 DOI: 10.1016/j.lrr.2015.12.001

Abstract

Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.

Keywords: Elderly patients; Hepatosplenic T-cell lymphoma; Immunodeficiency

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