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Curr Treat Options Gastroenterol. 2016 Mar;14(1):28-38. doi: 10.1007/s11938-016-0082-2.

Evaluation and Management of Infectious Esophagitis in Immunocompromised and Immunocompetent Individuals.

Current treatment options in gastroenterology

Nitin K Ahuja, John O Clarke

Affiliations

  1. Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, 4940 Eastern Avenue, A Building, Room 344B, Baltimore, MD, 21224, USA.
  2. Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, 4940 Eastern Avenue, A Building, Room 344B, Baltimore, MD, 21224, USA. [email protected].

PMID: 26847359 DOI: 10.1007/s11938-016-0082-2

Abstract

OPINION STATEMENT: Among the many inflammatory processes that may account for esophageal symptoms, infection represents an important etiologic category with numerous clinically relevant subdivisions. While features of the history and physical exam are informative, diagnosis often hinges on endoscopic visualization and histopathologic analysis. This chapter will review in series the most clinically relevant causative agents for infectious esophagitis, with specific diagnostic and therapeutic features of note divided into one of two immune milieus. Our discussion focuses primarily on Candida species, herpes simplex virus, and cytomegalovirus as the most common causes of infectious esophagitis while also addressing a number of less common pathogens worth keeping in mind.

Keywords: Candidiasis; Cytomegalovirus; Dysphagia; Esophagus; Herpes simplex; Odynophagia

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