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Igho OE. A 20-year retrospective study of histopathologic patterns of gonadal germ cell tumors in males in the University of Benin Teaching Hospital. Niger Med J. 2015;56(6):385-9doi: 10.4103/0300-1652.171619.
Igho, O. E. (2015). A 20-year retrospective study of histopathologic patterns of gonadal germ cell tumors in males in the University of Benin Teaching Hospital. Nigerian medical journal : journal of the Nigeria Medical Association, 56(6), 385-9. https://doi.org/10.4103/0300-1652.171619
Igho, Odokuma Emmanuel. "A 20-year retrospective study of histopathologic patterns of gonadal germ cell tumors in males in the University of Benin Teaching Hospital." Nigerian medical journal : journal of the Nigeria Medical Association vol. 56,6 (2015): 385-9. doi: https://doi.org/10.4103/0300-1652.171619
Igho OE. A 20-year retrospective study of histopathologic patterns of gonadal germ cell tumors in males in the University of Benin Teaching Hospital. Niger Med J. 2015 Nov-Dec;56(6):385-9. doi: 10.4103/0300-1652.171619. PMID: 26903694; PMCID: PMC4743286.
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Niger Med J. 2015 Nov-Dec;56(6):385-9. doi: 10.4103/0300-1652.171619.

A 20-year retrospective study of histopathologic patterns of gonadal germ cell tumors in males in the University of Benin Teaching Hospital.

Nigerian medical journal : journal of the Nigeria Medical Association

Odokuma Emmanuel Igho

Affiliations

  1. Department of Human Anatomy and Cell Biology, Delta State University, Abraka, Delta State, Nigeria.

PMID: 26903694 PMCID: PMC4743286 DOI: 10.4103/0300-1652.171619

Abstract

BACKGROUND: Localization of germ cells tumors to the gonads is not uncommon and has been shown to possess good prognosis with appropriate treatment. Studies on the prevalence and histopathologic features of these tumors in Nigerians are, however, rare. This study was, therefore, aimed at determining the pattern of gonadal germ cell tumors (GGCTs) in Benin and environs.

MATERIALS AND METHODS: This was a 20-year retrospective study conducted at the University of Benin Teaching Hospital 9-(UBTH), a tertiary health facility in Benin City. Data were obtained from the histopathology day book of the Department of Morbid Anatomy of the UBTH, and permission was obtained from the UBTH Ethics Committee protocol number ADM/E 22/A/VOL.VH/928 with results displayed in tables and figures.

RESULTS: Intratubular germ cell neoplasms (ITGN) was the most common GGCT with about 33.3% of the total and was distributed within the fourth to fifth decades of life; benign cystic teratoma and choriocarcinoma were observed to have a low occurrence with 8.3% each found in age groups 11-20 and 21-30 years, respectively. The studied gonadal lesions were most frequent at the left testis and were predominantly premalignant forms.

CONCLUSION: This was an index study on patterns of GGCTs in males in UBTH, and it showed that GGCTs in males were predominantly premalignant with ITGN as the most common type of testicular germ cell tumors.

Keywords: Gonadal; histopathology; male; premalignant; retrospective

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