Display options
Cite
Huh K, Joung JY, Jeong H, et al. Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient. Kidney Res Clin Pract. 2013;32(2):74-7doi: 10.1016/j.krcp.2013.04.003.
Huh, K., Joung, J. Y., Jeong, H., Je, D., Cho, Y. Y., Jang, H. R., & Huh, W. (2013). Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient. Kidney research and clinical practice, 32(2), 74-7. https://doi.org/10.1016/j.krcp.2013.04.003
Huh, Kyungmin, et al. "Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient." Kidney research and clinical practice vol. 32,2 (2013): 74-7. doi: https://doi.org/10.1016/j.krcp.2013.04.003
Huh K, Joung JY, Jeong H, Je D, Cho YY, Jang HR, Huh W. Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient. Kidney Res Clin Pract. 2013 Jun;32(2):74-7. doi: 10.1016/j.krcp.2013.04.003. Epub 2013 May 23. PMID: 26877917; PMCID: PMC4713917.
Copy Download .nbib Format: NLM
Share it on

Kidney Res Clin Pract. 2013 Jun;32(2):74-7. doi: 10.1016/j.krcp.2013.04.003. Epub 2013 May 23.

Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient.

Kidney research and clinical practice

Kyungmin Huh, Ji Young Joung, Hyemin Jeong, Dongmo Je, Yoon Young Cho, Hye Ryoun Jang, Wooseong Huh

Affiliations

  1. Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  2. Division of Nephrology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

PMID: 26877917 PMCID: PMC4713917 DOI: 10.1016/j.krcp.2013.04.003

Abstract

Colchicine is a relatively safe medication that is widely used for both prevention and treatment of gout attack. However, serious adverse events, including myoneuropathy and multiorgan failure, have been reported. We report a case of colchicine-induced myoneuropathy in a female kidney transplant recipient who had been taking cyclosporine. She developed gastrointestinal discomfort and paresthesia 5 days after the initiation of colchicine. She showed signs of myoneuropathy, and hepatic and renal injury. Colchicine toxicity was suspected, and colchicine was discontinued. Her symptoms and laboratory findings improved gradually. Literature was reviewed for previous reports of colchicine-induced myoneuropathy in solid organ transplant recipients.

Keywords: Colchicine; Cyclosporine; Gout; Myoneuropathy; Renal transplant

References

  1. Nephrol Dial Transplant. 1997 Nov;12(11):2389-92 - PubMed
  2. J Nephrol. 2003 May-Jun;16(3):421-5 - PubMed
  3. N Engl J Med. 1989 Aug 3;321(5):287-92 - PubMed
  4. Clin Neurol Neurosurg. 1997 Dec;99(4):266-70 - PubMed
  5. Transplant Proc. 1999 Aug;31(5):2157-8 - PubMed
  6. Clin Toxicol (Phila). 2008 Nov;46(9):827-30 - PubMed
  7. Arthritis Rheum. 2011 Aug;63(8):2226-37 - PubMed
  8. Transpl Int. 2002 Jul;15(7):374-6 - PubMed
  9. J Clin Rheumatol. 2011 Jan;17(1):28-30 - PubMed
  10. J Pharmacol Exp Ther. 1992 Apr;261(1):50-5 - PubMed
  11. Pharmacotherapy. 2004 Dec;24(12):1784-92 - PubMed
  12. J Rheumatol. 2000 Jun;27(6):1334-7 - PubMed
  13. J Korean Med Sci. 1997 Apr;12(2):160-1 - PubMed
  14. N Z Med J. 1997 Sep 12;110(1051):343 - PubMed
  15. N Engl J Med. 1987 Jun 18;316(25):1562-8 - PubMed

Publication Types