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Ann Med Surg (Lond). 2015 Sep 03;4(4):371-5. doi: 10.1016/j.amsu.2015.08.010. eCollection 2015 Dec.

Quality of life after subtotal gastrectomy for gastric cancer: Does restoration method matter? - A retrospective cohort study.

Annals of medicine and surgery (2012)

Edgaras Smolskas, Raimundas Lunevicius, Narimantas Evaldas Samalavicius

Affiliations

  1. Vilnius University Hospital Santariskes Clinics, 2 Santariskiu Str, LT-08661, Vilnius, Lithuania.
  2. Emergency General Surgery and Major Trauma Centre, General Surgery Department, Aintree University Hospital NHS Foundation Trust, Lower Lane, Liverpool, L9 7AL, United Kingdom.
  3. Clinic of Internal Diseases, Family Medicine and Oncology of Medical Faculty, Institute of Oncology, Vilnius University, 1 Santariskiu Str, LT-08660, Vilnius, Lithuania.

PMID: 26904188 PMCID: PMC4720718 DOI: 10.1016/j.amsu.2015.08.010

Abstract

INTRODUCTION: The aim of this study was to evaluate the impact on the quality of life (QoL) status of three gastrointestinal continuity restoration methods following a subtotal gastrectomy in patients with gastric cancer.

METHODS: QoL data from 153 patients were obtained and evaluated in this retrospective cross-sectional case series study. A list of patients who responded to questionnaires on QoL was stratified into three arms based on which gastrointestinal continuity restoration method was used - Billroth I (n = 37), Roux-en-Y (n = 15), and Balfour (n = 101).

RESULTS: The mean global health status scores for the patients following the Billroth I, Roux-en-Y and Balfour reconstructive surgery arms were 62 ± 20.09, 61 ± 24.08 and 56 ± 21.2, respectively, (p = 0.182). The mean scores of the functional scales were not lower than 60 in any of the patient groups. For physical, role, cognitive, social functional scales, the Billroth I method had the best mean QoL score. Comparisons of the global QoL, functional activities, and majority of the postgastrectomy symptom scores at different time points after the surgeries (6-12 months vs > 1 year) did not reveal major significant differences between the groups. However, the results highlighted trends and ranked the gastrointestinal continuity restoration methods over time.

CONCLUSIONS: The best QoL scores were obtained from the patients who underwent the Billroth I surgery. The Roux-en-Y method was better than the Balfour method 6-12 months after surgery. However, the Balfour method was better than the Roux-en-Y after one year. Further prospective randomized controlled trials are needed.

Keywords: Distal gastrectomy; Gastric cancer; Quality of life; Stomach neoplasms

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