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Champer J, Ito JI, Clemons KV, et al. Proteomic Analysis of Pathogenic Fungi Reveals Highly Expressed Conserved Cell Wall Proteins. J Fungi (Basel). 2016;2(1)doi: 10.3390/jof2010006.
Champer, J., Ito, J. I., Clemons, K. V., Stevens, D. A., & Kalkum, M. (2016). Proteomic Analysis of Pathogenic Fungi Reveals Highly Expressed Conserved Cell Wall Proteins. Journal of fungi (Basel, Switzerland), 2(1), . https://doi.org/10.3390/jof2010006
Champer, Jackson, et al. "Proteomic Analysis of Pathogenic Fungi Reveals Highly Expressed Conserved Cell Wall Proteins." Journal of fungi (Basel, Switzerland) vol. 2,1 (2016). doi: https://doi.org/10.3390/jof2010006
Champer J, Ito JI, Clemons KV, Stevens DA, Kalkum M. Proteomic Analysis of Pathogenic Fungi Reveals Highly Expressed Conserved Cell Wall Proteins. J Fungi (Basel). 2016 Mar;2(1). doi: 10.3390/jof2010006. Epub 2016 Jan 12. PMID: 26878023; PMCID: PMC4747415.
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J Fungi (Basel). 2016 Mar;2(1). doi: 10.3390/jof2010006. Epub 2016 Jan 12.

Proteomic Analysis of Pathogenic Fungi Reveals Highly Expressed Conserved Cell Wall Proteins.

Journal of fungi (Basel, Switzerland)

Jackson Champer, James I Ito, Karl V Clemons, David A Stevens, Markus Kalkum

Affiliations

  1. Department of Molecular Immunology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
  2. Division of Infectious Diseases, City of Hope National Medical Center, Duarte, CA 91010, USA.
  3. California Institute for Medical Research, San Jose, CA 95128, USA; Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA 94305, USA.

PMID: 26878023 PMCID: PMC4747415 DOI: 10.3390/jof2010006

Abstract

We are presenting a quantitative proteomics tally of the most commonly expressed conserved fungal proteins of the cytosol, the cell wall, and the secretome. It was our goal to identify fungi-typical proteins that do not share significant homology with human proteins. Such fungal proteins are of interest to the development of vaccines or drug targets. Protein samples were derived from 13 fungal species, cultured in rich or in minimal media; these included clinical isolates of

Keywords: Aspergillus; Candida; fungal pathogens; proteomics; vaccine candidates

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