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Kujawski K, Stasiak M, Rysz J. Qualification for endoscopic retrograde cholangiopancreatography in the diagnosis and treatment of extrahepatic cholestasis caused by choledocholithiasis. Arch Med Sci. 2015;11(6):1213-6doi: 10.5114/aoms.2015.56347.
Kujawski, K., Stasiak, M., & Rysz, J. (2015). Qualification for endoscopic retrograde cholangiopancreatography in the diagnosis and treatment of extrahepatic cholestasis caused by choledocholithiasis. Archives of medical science : AMS, 11(6), 1213-6. https://doi.org/10.5114/aoms.2015.56347
Kujawski, Krzysztof, et al. "Qualification for endoscopic retrograde cholangiopancreatography in the diagnosis and treatment of extrahepatic cholestasis caused by choledocholithiasis." Archives of medical science : AMS vol. 11,6 (2015): 1213-6. doi: https://doi.org/10.5114/aoms.2015.56347
Kujawski K, Stasiak M, Rysz J. Qualification for endoscopic retrograde cholangiopancreatography in the diagnosis and treatment of extrahepatic cholestasis caused by choledocholithiasis. Arch Med Sci. 2015 Dec 10;11(6):1213-6. doi: 10.5114/aoms.2015.56347. Epub 2015 Dec 11. PMID: 26788082; PMCID: PMC4697055.
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Arch Med Sci. 2015 Dec 10;11(6):1213-6. doi: 10.5114/aoms.2015.56347. Epub 2015 Dec 11.

Qualification for endoscopic retrograde cholangiopancreatography in the diagnosis and treatment of extrahepatic cholestasis caused by choledocholithiasis.

Archives of medical science : AMS

Krzysztof Kujawski, Magdalena Stasiak, Jacek Rysz

Affiliations

  1. Gastrointestinal Endoscopy Laboratory, WAM University Hospital, Medical University of Lodz, Lodz, Poland; Department of Nephrology, Hypertension and Family Medicine, Medical University of Lodz, Lodz, Poland.
  2. Department of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital-Research Institute, Lodz, Poland.
  3. Department of Nephrology, Hypertension and Family Medicine, Medical University of Lodz, Lodz, Poland.

PMID: 26788082 PMCID: PMC4697055 DOI: 10.5114/aoms.2015.56347

Abstract

INTRODUCTION: Choledocholithiasis, being the most common cause of extrahepatic cholestasis, is diagnosed on the basis of clinical symptoms, laboratory findings, and imaging results. An important diagnostic and also therapeutic procedure performed in patients with choledocholithiasis is retrograde cholangiopancreatography (ERCP). However, due to the high rate of complications associated with ERCP, the decision on its implementation should be preceded by a thorough analysis of the case, aimed at confirmation of the diagnosis.

MATERIAL AND METHODS: The present study is a retrospective analysis of 86 patients qualified for ERCP due to suspected choledocholithiasis. The diagnosis was based on clinical symptoms and/or laboratory and/or imaging results. The presence of one or more of the three abovementioned criteria was a key to classify patients in one of three risk groups of choledocholithiasis: high, intermediate and low.

RESULTS: In the high-risk group, where choledocholithiasis was confirmed by clinical symptoms, laboratory findings and results of imaging tests, the accuracy of diagnosis was 100%. In the intermediate-risk group - choledocholithiasis diagnosed on the basis of clinical symptoms and laboratory results - the accuracy of diagnosis was approximately 81.5% (p < 0.05). In the low-risk group, in which choledocholithiasis was diagnosed only on the basis of clinical symptoms, diagnosis accuracy was approximately 50% (p < 0.05).

CONCLUSIONS: The combination of clinical symptoms, laboratory tests and imaging findings allows patients to be classified into three risk groups of choledocholithiasis: high, intermediate and low. Taking into account the probability of choledocholithiasis and the risk of ERCP complications, only patients from high and intermediate risk groups should be qualified for the procedure.

Keywords: choledocholithiasis; endoscopic retrograde cholangiopancreatography; extrahepatic cholestasis

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