Display options
Cite
Roberts WM, Augustine SB, Lawton KJ, et al. . Elife. 2016;5doi: 10.7554/eLife.12572.
Roberts, W. M., Augustine, S. B., Lawton, K. J., Lindsay, T. H., Thiele, T. R., Izquierdo, E. J., Faumont, S., Lindsay, R. A., Britton, M. C., Pokala, N., Bargmann, C. I., & Lockery, S. R. (2016). . eLife, 5. https://doi.org/10.7554/eLife.12572
Roberts, William M, et al. "." eLife vol. 5 (2016). doi: https://doi.org/10.7554/eLife.12572
Roberts WM, Augustine SB, Lawton KJ, Lindsay TH, Thiele TR, Izquierdo EJ, Faumont S, Lindsay RA, Britton MC, Pokala N, Bargmann CI, Lockery SR. . Elife. 2016 Jan 29;5. doi: 10.7554/eLife.12572. PMID: 26824391; PMCID: PMC4798983.
Copy Download .nbib Format: NLM
Share it on

Elife. 2016 Jan 29;5. doi: 10.7554/eLife.12572.

[No title available]

eLife

William M Roberts, Steven B Augustine, Kristy J Lawton, Theodore H Lindsay, Tod R Thiele, Eduardo J Izquierdo, Serge Faumont, Rebecca A Lindsay, Matthew Cale Britton, Navin Pokala, Cornelia I Bargmann, Shawn R Lockery

Affiliations

  1. Institute of Neuroscience, University of Oregon, Eugene, United States.
  2. School of Nursing, University of Pennsylvania, Philadelphia, United States.
  3. Biology Department, Reed College, Portland, United States.
  4. Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
  5. Department of Biological Sciences, University of Toronto, Toronto, Canada.
  6. Cognitive Science Program, Indiana University, Bloomington, United States.
  7. Department of Ophthalmology, The Vision Center, Children's Hospital Los Angeles, Los Angeles, United States.
  8. Department of Neurology, University of Minnesota, Minneapolis, United States.
  9. Department of Life Sciences, New York Institute of Technology, Old Westbury, United States.
  10. Howard Hughes Medical Institute, Rockefeller University, New York, United States.

PMID: 26824391 PMCID: PMC4798983 DOI: 10.7554/eLife.12572

Abstract

Random search is a behavioral strategy used by organisms from bacteria to humans to locate food that is randomly distributed and undetectable at a distance. We investigated this behavior in the nematode

© 2016, Roberts et al.

Keywords: C. elegans; computational biology; hidden Markov model; locomotion; neuroscience; spatial orientation; stochastic neural network; systems biology

Conflict of interest statement

WR, SA, KL, TL, TT, EI, SF, RL, MB, NP, CB, SL No competing interests declared

References

  1. Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10477-82 - PubMed
  2. Nature. 1972 Oct 27;239(5374):500-4 - PubMed
  3. PLoS One. 2012;7(8):e43164 - PubMed
  4. Proc Natl Acad Sci U S A. 2012 May 8;109(19):7499-504 - PubMed
  5. Cell. 1982 Nov;31(1):215-26 - PubMed
  6. J Neurophysiol. 2000 Feb;83(2):853-63 - PubMed
  7. Neuron. 2015 Apr 22;86(2):428-41 - PubMed
  8. Nat Commun. 2014 Nov 21;5:5579 - PubMed
  9. Science. 2009 Jan 16;323(5912):382-4 - PubMed
  10. Neuron. 2002 Jul 18;35(2):307-18 - PubMed
  11. Nature. 2007 Nov 1;450(7166):63-70 - PubMed
  12. Elife. 2015 Dec 25;4: - PubMed
  13. PLoS Comput Biol. 2008 Apr 25;4(4):e1000028 - PubMed
  14. Proc Natl Acad Sci U S A. 2012 May 8;109(19):7169-74 - PubMed
  15. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7286-9 - PubMed
  16. Nature. 2008 Jul 3;454(7200):114-7 - PubMed
  17. J Neurosci. 2002 Jul 1;22(13):5727-33 - PubMed
  18. Methods Cell Biol. 1995;48:451-82 - PubMed
  19. Cell. 2015 Apr 9;161(2):215-27 - PubMed
  20. J R Soc Interface. 2014 Jan 15;11(92):20131092 - PubMed
  21. J Neurosci. 2004 Aug 25;24(34):7427-34 - PubMed
  22. Nat Commun. 2014 Oct 10;5:5155 - PubMed
  23. J Neurobiol. 2003 Aug;56(2):178-97 - PubMed
  24. Elife. 2016 Jan 29;5: - PubMed
  25. Nat Methods. 2014 Jul;11(7):727-730 - PubMed
  26. PLoS Genet. 2014 Aug 28;10(8):e1004584 - PubMed
  27. J Theor Biol. 2014 Oct 7;358:179-93 - PubMed
  28. J Anim Ecol. 2012 Mar;81(2):432-42 - PubMed
  29. Phys Rev E Stat Nonlin Soft Matter Phys. 2014 May;89(5):052805 - PubMed
  30. Neuron. 2011 Nov 17;72(4):572-86 - PubMed
  31. J Neurosci. 1999 Nov 1;19(21):9557-69 - PubMed
  32. Methods Cell Biol. 1995;48:225-50 - PubMed
  33. J Neurosci. 2003 Jun 15;23(12):5319-28 - PubMed
  34. J Neurophysiol. 2003 Oct;90(4):2190-204 - PubMed
  35. Ecol Appl. 2007 Mar;17(2):331-7 - PubMed
  36. PLoS Comput Biol. 2011 Feb 03;7(2):e1001066 - PubMed
  37. PLoS One. 2012;7(3):e32360 - PubMed
  38. Nature. 2010 Jun 24;465(7301):1066-9 - PubMed
  39. Methods Enzymol. 1998;293:201-17 - PubMed
  40. Neuron. 2013 Mar 20;77(6):1069-82 - PubMed
  41. Philos Trans R Soc Lond B Biol Sci. 2015 Sep 19;370(1677):20140212 - PubMed
  42. Neuron. 2008 Nov 6;60(3):489-95 - PubMed
  43. J Exp Biol. 1946 Dec;23(2):101-20 - PubMed
  44. Neuron. 1999 Oct;24(2):347-61 - PubMed
  45. J Neurosci. 2013 Mar 20;33(12):5319-25 - PubMed
  46. Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17545-8 - PubMed
  47. J Neurosci. 1985 Apr;5(4):956-64 - PubMed
  48. J Neurophysiol. 2000 Feb;83(2):712-22 - PubMed
  49. Nat Methods. 2013 Oct;10(10):1013-20 - PubMed
  50. Neuron. 2014 Jun 4;82(5):1115-28 - PubMed
  51. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1074-81 - PubMed
  52. Curr Biol. 2001 Jun 5;11(11):809-21 - PubMed
  53. J Exp Biol. 1964 Mar;41:135-54 - PubMed
  54. PLoS One. 2010 Nov 16;5(11):e13914 - PubMed
  55. J Exp Zool B Mol Dev Evol. 2009 May 15;312B(3):224-30 - PubMed
  56. Cell. 2013 Aug 29;154(5):1023-1035 - PubMed
  57. Science. 2008 Oct 17;322(5900):460-4 - PubMed
  58. Elife. 2014 Dec 09;3: - PubMed
  59. Elife. 2015 Mar 30;4: - PubMed
  60. J Neurosci. 2004 Feb 4;24(5):1217-25 - PubMed
  61. J Neurosci Methods. 2010 Aug 15;191(1):90-3 - PubMed
  62. Nat Commun. 2011;2:306 - PubMed
  63. Neuron. 2010 Dec 22;68(6):1023-42 - PubMed
  64. Philos Trans R Soc Lond B Biol Sci. 1986 Nov 12;314(1165):1-340 - PubMed
  65. Genetics. 1974 May;77(1):71-94 - PubMed
  66. PLoS One. 2013 Nov 05;8(11):e78535 - PubMed
  67. BMC Neurosci. 2013 Jul 03;14:66 - PubMed
  68. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3184-91 - PubMed
  69. Proc Natl Acad Sci U S A. 1982 Apr;79(8):2554-8 - PubMed
  70. Nature. 2011 Apr 21;472(7343):313-8 - PubMed
  71. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1082-8 - PubMed
  72. J Neurosci. 2009 Sep 23;29(38):11904-11 - PubMed
  73. J Neurosci. 2009 Apr 29;29(17):5370-80 - PubMed
  74. Nature. 2012 Oct 11;490(7419):273-7 - PubMed
  75. PLoS One. 2009 Oct 23;4(10):e7584 - PubMed
  76. Curr Biol. 2008 Nov 11;18(21):1694-9 - PubMed
  77. Curr Opin Neurobiol. 2012 Aug;22(4):580-91 - PubMed
  78. J Exp Biol. 2006 Jan;209(Pt 1):89-102 - PubMed
  79. Front Comput Neurosci. 2013 Oct 02;7:128 - PubMed
  80. Nature. 1995 Nov 2;378(6552):82-5 - PubMed
  81. J Neurosci. 1996 Jun 15;16(12):4017-31 - PubMed
  82. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2770-5 - PubMed
  83. Neurosci Res. 2000 Sep;38(1):71-83 - PubMed
  84. Neuron. 2002 Dec 19;36(6):1091-102 - PubMed
  85. Eur J Neurosci. 2000 Nov;12(11):4081-92 - PubMed
  86. Cell. 2011 Nov 11;147(4):922-33 - PubMed
  87. Neuron. 2001 Aug 30;31(4):617-30 - PubMed
  88. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2295-300 - PubMed
  89. Cell. 2015 Oct 22;163(3):656-69 - PubMed
  90. Phys Rev Lett. 1994 Nov 28;73(22):2946-2949 - PubMed
  91. PLoS One. 2011;6(9):e24666 - PubMed
  92. BMC Genet. 2005 Feb 07;6:5 - PubMed
  93. Neurosci Res. 2004 Sep;50(1):103-11 - PubMed
  94. Curr Opin Neurobiol. 2011 Oct;21(5):782-90 - PubMed
  95. Nature. 2006 Mar 30;440(7084):684-7 - PubMed
  96. Nat Commun. 2015 Feb 26;6:6323 - PubMed
  97. Nat Neurosci. 2008 Aug;11(8):865-7 - PubMed

Publication Types

Grant support