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Geesala R, Bar N, Dhoke NR, et al. Data on bone marrow stem cells delivery using porous polymer scaffold. Data Brief. 2015;6:221-8doi: 10.1016/j.dib.2015.12.014.
Geesala, R., Bar, N., Dhoke, N. R., Basak, P., & Das, A. (2016). Data on bone marrow stem cells delivery using porous polymer scaffold. Data in brief, 6221-8. https://doi.org/10.1016/j.dib.2015.12.014
Geesala, Ramasatyaveni, et al. "Data on bone marrow stem cells delivery using porous polymer scaffold." Data in brief vol. 6 (2016): 221-8. doi: https://doi.org/10.1016/j.dib.2015.12.014
Geesala R, Bar N, Dhoke NR, Basak P, Das A. Data on bone marrow stem cells delivery using porous polymer scaffold. Data Brief. 2015 Dec 15;6:221-8. doi: 10.1016/j.dib.2015.12.014. eCollection 2016 Mar. PMID: 26862563; PMCID: PMC4707184.
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Data Brief. 2015 Dec 15;6:221-8. doi: 10.1016/j.dib.2015.12.014. eCollection 2016 Mar.

Data on bone marrow stem cells delivery using porous polymer scaffold.

Data in brief

Ramasatyaveni Geesala, Nimai Bar, Neha R Dhoke, Pratyay Basak, Amitava Das

Affiliations

  1. Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500007, India; Academy of Scientific & Innovative Research (AcSIR), 2 Rafi Marg, New Delhi 110001, India.
  2. Nanomaterials Laboratory, Division of Inorganic and Physical Chemistry, CSIR-Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500007, India; Academy of Scientific & Innovative Research (AcSIR), 2 Rafi Marg, New Delhi 110001, India.

PMID: 26862563 PMCID: PMC4707184 DOI: 10.1016/j.dib.2015.12.014

Abstract

Low bioavailability and/or survival at the injury site of transplanted stem cells necessitate its delivery using a biocompatible, biodegradable cell delivery vehicle. In this dataset, we report the application of a porous biocompatible, biodegradable polymer network that successfully delivers bone marrow stem cells (BMSCs) at the wound site of a murine excisional splint wound model. In this data article, we are providing the additional data of the reference article "Porous polymer scaffold for on-site delivery of stem cells - protects from oxidative stress and potentiates wound tissue repair" (Ramasatyaveni et al., 2016) [1]. This data consists of the characterization of bone marrow stem cells (BMSCs) showing the pluripotency and stem cell-specific surface markers. Image analysis of the cellular penetration into PEG-PU polymer network and the mechanism via enzymatic activation of MMP-2 and MMP-13 are reported. In addition, we provide a comparison of various routes of transplantation-mediated BMSCs engraftment in the murine model using bone marrow transplantation chimeras. Furthermore, we included in this dataset the engraftment of BMSCs expressing Sca-1(+)Lin(-)CD133(+)CD90.2(+) in post-surgery day 10.

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