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Data Brief. 2015 Dec 17;6:295-310. doi: 10.1016/j.dib.2015.12.021. eCollection 2016 Mar.

Data supporting that miR-92a suppresses angiogenic activity of adipose-derived mesenchymal stromal cells by down-regulating hepatocyte growth factor.

Data in brief

Anastassia Efimenko, Georgiy Sagaradze, Zhanna Akopyan, Tatiana Lopatina, Natalia Kalinina

Affiliations

  1. Faculty of Medicine, Lomonosov Moscow State University, 31-5, Lomonosovsky av, Moscow 119191 Russia.

PMID: 26862575 PMCID: PMC4706626 DOI: 10.1016/j.dib.2015.12.021

Abstract

This article contains the full list of miRNAs expressed in cultured mesenchymal stromal cells, which were isolated from human adipose tissue. We provide here data regarding the effect of miR-92a overexpression on MSCs viability and cellular content of HGF and angiopoietin-1. These are followed by the data regarding the effect of conditioned medium of MSC transfected with pre-miR-92a, anti-miR-92a or scramble oligos on HUVEC viability as well as their tube formation efficiency. We also demonstrate here data regarding the effect of extracellular vesicle depletion from MSCs conditioned medium on its ability to stimulate the tube formation by HUVEC. Data interpretation and discussion can be found in Kalinina et al. (2015) [1].

Keywords: Capillary-like tube formation; Cell viability; Mir-92a; Nucleofection

References

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  2. Exp Cell Res. 2015 Nov 15;339(1):61-6 - PubMed
  3. J Clin Invest. 1973 Nov;52(11):2745-56 - PubMed

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