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Endocrinol Metab Clin North Am. 2016 Mar;45(1):55-63. doi: 10.1016/j.ecl.2015.09.004.

Dyslipidemia in Pregnancy.

Endocrinology and metabolism clinics of North America

Robert Wild, Elizabeth A Weedin, Don Wilson

Affiliations

  1. Section of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, 1100 N Lindsay Ave, Oklahoma City, OK 73104, USA.
  2. Section of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, 1100 N Lindsay Ave, Oklahoma City, OK 73104, USA. Electronic address: [email protected].
  3. Department of Pediatric Endocrinology, Cook Children's Medical Center, 1500 Cooper Street, Fort Worth, TX 76104, USA.

PMID: 26892997 DOI: 10.1016/j.ecl.2015.09.004

Abstract

"Recent studies have revealed evidence that poorly controlled cholesterol, triglycerides, and their metabolites during pregnancy may be associated with cardiometabolic dysfunction and have significant detrimental fetal and maternal vascular consequences. Cardiometabolic dysfunction during pregnancy may not only contribute to long-term effects of the mother and child's vascular health but also potentially create cardiovascular risk for generational offspring. This article provides updates on this rapidly expanding and multifaceted topic and reviews new insight regarding why recognition of this disordered maternal cholesterol and triglyceride metabolism is likely to have long-term effect on the increasing atherosclerotic burden of the burgeoning population."

Published by Elsevier Inc.

Keywords: Dyslipidemia; Fetal metabolism; Hyperlipidemia; Metabolic syndrome; Pregnancy

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