Display options
Cite
Czech SJ, Orsillo SM, Pirraglia PA, et al. Association Between Specific Depression Symptoms and Glycemic Control Among Patients With Comorbid Type 2 Diabetes and Provisional Depression. Prim Care Companion CNS Disord. 2015;17(5)doi: 10.4088/PCC.14m01754.
Czech, S. J., Orsillo, S. M., Pirraglia, P. A., English, T. M., & Connell, A. J. (2015). Association Between Specific Depression Symptoms and Glycemic Control Among Patients With Comorbid Type 2 Diabetes and Provisional Depression. The primary care companion for CNS disorders, 17(5), . https://doi.org/10.4088/PCC.14m01754
Czech, Stephanie J, et al. "Association Between Specific Depression Symptoms and Glycemic Control Among Patients With Comorbid Type 2 Diabetes and Provisional Depression." The primary care companion for CNS disorders vol. 17,5 (2015). doi: https://doi.org/10.4088/PCC.14m01754
Czech SJ, Orsillo SM, Pirraglia PA, English TM, Connell AJ. Association Between Specific Depression Symptoms and Glycemic Control Among Patients With Comorbid Type 2 Diabetes and Provisional Depression. Prim Care Companion CNS Disord. 2015 Oct 15;17(5). doi: 10.4088/PCC.14m01754. eCollection 2015. PMID: 26835160; PMCID: PMC4732304.
Copy Download .nbib Format: NLM
Share it on

Prim Care Companion CNS Disord. 2015 Oct 15;17(5). doi: 10.4088/PCC.14m01754. eCollection 2015.

Association Between Specific Depression Symptoms and Glycemic Control Among Patients With Comorbid Type 2 Diabetes and Provisional Depression.

The primary care companion for CNS disorders

Stephanie J Czech, Susan M Orsillo, Paul A Pirraglia, Thomas M English, Alexa J Connell

Affiliations

  1. Department of Psychiatry, Rhode Island Hospital, Providence.
  2. Department of Psychology, Suffolk University, Boston, Massachusetts.
  3. Primary Care, Providence VA Medical Center and Alpert Medical School, Brown University, Providence, Rhode Island.
  4. Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester.
  5. Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester.

PMID: 26835160 PMCID: PMC4732304 DOI: 10.4088/PCC.14m01754

Abstract

OBJECTIVE: To determine whether specific depression symptoms are associated with glycemic control independent of potential demographic and clinical covariates among primary care patients with comorbid type 2 diabetes and provisional threshold or subthreshold depression.

METHOD: We examined a convenience sample of patients diagnosed with type 2 diabetes and provisional threshold or subthreshold depression (N = 82) at 2 family health centers. Cases were identified using a population-based registry of patients diagnosed with type 2 diabetes (ICD-9 codes 250.00 for controlled type 2 diabetes and 250.02 for uncontrolled type 2 diabetes). Data from patients with a primary care provider appointment from the beginning of April 2011 through the end of June 2012 and with at least one 9-item Patient Health Questionnaire (PHQ-9) depression screener and a glycated hemoglobin A1c (HbA1c) laboratory test between 2 weeks before and 10 weeks after PHQ-9 screening were eligible for inclusion. We defined provisional threshold or subthreshold depression using PHQ-9 scoring criteria, which were designed to yield provisional diagnostic information about major depressive disorder based on DSM-5 diagnostic criteria.

RESULTS: Patients reporting higher severity of sleep problems on the PHQ-9 had significantly higher HbA1c levels (mean = 8.48, SD = 2.17) compared to patients reporting lower severity or absence of this symptom (mean = 7.19, SD = 1.34, t 48.88 = -3.13, P = .003). Problems with sleep contributed unique variance on glycemic control (β = 0.27, P = .02) when controlling for potential clinical and demographic covariates, with those reporting more sleep difficulties having higher HbA1c levels.

CONCLUSIONS: For patients with type 2 diabetes and provisional threshold or subthreshold depression, it may be prudent to aggressively address sleep problems as a potential mechanism toward improving diabetes control.

References

  1. Diabet Med. 2013 Mar;30(3):e115-22 - PubMed
  2. J Gen Intern Med. 2001 Sep;16(9):606-13 - PubMed
  3. Diabetes Care. 2003 Mar;26(3):702-9 - PubMed
  4. Psychosom Med. 2001 Jul-Aug;63(4):619-30 - PubMed
  5. Arch Gen Psychiatry. 2010 Mar;67(3):220-9 - PubMed
  6. Diabetes Care. 2011 Jun;34(6):e61-99 - PubMed
  7. JAMA. 2003 Jun 18;289(23):3095-105 - PubMed
  8. Sleep. 2008 Apr;31(4):489-95 - PubMed
  9. Am J Respir Crit Care Med. 2010 Mar 1;181(5):507-13 - PubMed
  10. JAMA. 1999 Nov 10;282(18):1737-44 - PubMed
  11. Sleep Med Rev. 2004 Feb;8(1):19-30 - PubMed
  12. Diabetes Care. 2014 Jan;37 Suppl 1:S14-80 - PubMed
  13. J Endocrinol Invest. 2005 Sep;28(8):683-91 - PubMed
  14. Am J Manag Care. 2008 Jan;14(1):15-23 - PubMed
  15. J Clin Psychiatry. 2010 Dec;71(12):1582-9 - PubMed
  16. Psychoneuroendocrinology. 2011 Oct;36(9):1276-86 - PubMed
  17. Biol Psychiatry. 2003 Aug 1;54(3):317-29 - PubMed
  18. J Chronic Dis. 1987;40(5):373-83 - PubMed
  19. Endocr Pract. 2007 Jul-Aug;13(4):355-62 - PubMed
  20. Med Care. 2005 Nov;43(11):1130-9 - PubMed
  21. J Diabetes Complications. 2005 Mar-Apr;19(2):113-22 - PubMed
  22. Nat Rev Endocrinol. 2009 May;5(5):253-61 - PubMed
  23. Acta Med Scand. 1987;221(5):475-81 - PubMed
  24. Diabetes Care. 2006 Apr;29(4):830-5 - PubMed
  25. Drugs. 2009;69 Suppl 2:13-27 - PubMed
  26. Diabetes Res Clin Pract. 1994 Apr;23(3):183-6 - PubMed
  27. Biol Psychiatry. 2006 Jun 1;59(11):1052-60 - PubMed
  28. Arch Intern Med. 2000 Nov 27;160(21):3278-85 - PubMed
  29. J Clin Psychiatry. 2011 Dec;72(12):1651-8 - PubMed
  30. Diabetes Care. 1996 Mar;19(3):204-10 - PubMed
  31. Diabetes Care. 2004 Apr;27(4):914-20 - PubMed
  32. Qual Life Res. 1997 Jan;6(1):11-20 - PubMed
  33. Psychosomatics. 2011 Jan-Feb;52(1):1-18 - PubMed
  34. J Gen Intern Med. 2004 Dec;19(12):1192-9 - PubMed
  35. Arch Intern Med. 2006 Sep 18;166(16):1768-74 - PubMed
  36. Curr Psychiatry Rep. 2009 Dec;11(6):437-42 - PubMed
  37. Health Psychol. 1989;8(1):45-59 - PubMed
  38. Psychosom Med. 2007 Apr;69(3):235-41 - PubMed
  39. Diabetes Res Clin Pract. 2011 Feb;91(2):129-37 - PubMed
  40. J Psychosom Res. 2002 Oct;53(4):917-24 - PubMed
  41. Diabet Med. 2006 Nov;23(11):1165-73 - PubMed
  42. Diabetes Care. 2000 Jul;23(7):934-42 - PubMed
  43. Am J Prev Med. 2006 May;30(5):371-7 - PubMed
  44. J Gen Intern Med. 2007 Nov;22(11):1596-602 - PubMed
  45. Endocrinol Metab Clin North Am. 2002 Mar;31(1):37-62, vi - PubMed
  46. Neuropsychopharmacology. 2004 Oct;29(10):1765-81 - PubMed

Publication Types