Display options
Cite
Chandak S, Agarwal A, Shukla A, et al. A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis. J Clin Diagn Res. 2016;10(1):TD06-7doi: 10.7860/JCDR/2016/14900.7031.
Chandak, S., Agarwal, A., Shukla, A., & Joon, P. (2016). A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis. Journal of clinical and diagnostic research : JCDR, 10(1), TD06-7. https://doi.org/10.7860/JCDR/2016/14900.7031
Chandak, Shruti, et al. "A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis." Journal of clinical and diagnostic research : JCDR vol. 10,1 (2016): TD06-7. doi: https://doi.org/10.7860/JCDR/2016/14900.7031
Chandak S, Agarwal A, Shukla A, Joon P. A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis. J Clin Diagn Res. 2016 Jan;10(1):TD06-7. doi: 10.7860/JCDR/2016/14900.7031. Epub 2016 Jan 01. PMID: 26894145; PMCID: PMC4740673.
Copy Download .nbib Format: NLM
Share it on

J Clin Diagn Res. 2016 Jan;10(1):TD06-7. doi: 10.7860/JCDR/2016/14900.7031. Epub 2016 Jan 01.

A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis.

Journal of clinical and diagnostic research : JCDR

Shruti Chandak, Arjit Agarwal, Arvind Shukla, Pawan Joon

Affiliations

  1. Associate Professor, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College , Moradabad, Uttar Pradesh, India .
  2. Assistant Professor, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College , Moradabad, Uttar Pradesh, India .
  3. Professor, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College , Moradabad, Uttar Pradesh, India .
  4. Junior Resident, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College , Moradabad, Uttar Pradesh, India .

PMID: 26894145 PMCID: PMC4740673 DOI: 10.7860/JCDR/2016/14900.7031

Abstract

Metronidazole is a very widely used drug for the treatment of multiple ailments caused by anaerobic bacteria as well as some protozoan parasites. Though its usual side effects are not very serious, yet sometimes it may cause profound adverse effects like neurotoxicity. We present here a case of liver abscess. The patient was treated for a long time with metronidazole and developed sudden onset neurotoxicity which was diagnosed by MRI. The present case also highlights the need of vigilant monitoring of patients on metronidazole for symptoms of neurotoxicity and the usefulness of MRI for diagnosis of the same.

Keywords: Dentate nucleus; Liver abscess; MRI brain; Metronidazole toxicity

References

  1. Int J Clin Pharmacol Res. 1999;19(3):83-8 - PubMed
  2. BMJ. 2001 Mar 3;322(7285):537-40 - PubMed
  3. J Appl Toxicol. 2007 Jul-Aug;27(4):380-90 - PubMed
  4. AJNR Am J Neuroradiol. 2007 Oct;28(9):1652-8 - PubMed
  5. Indian J Radiol Imaging. 2010 Aug;20(3):195-7 - PubMed
  6. J Med Case Rep. 2011 Feb 14;5:63 - PubMed
  7. Neurol India. 2011 Sep-Oct;59(5):743-7 - PubMed
  8. J Clin Med Res. 2012 Aug;4(4):295-8 - PubMed
  9. Ann Indian Acad Neurol. 2013 Oct;16(4):569-71 - PubMed
  10. N Z Med J. 2014 May 02;127(1393):120-2 - PubMed
  11. Radiol Case Rep. 2015 Dec 07;3(4):239 - PubMed
  12. Neurology. 1995 Mar;45(3 Pt 1):588-9 - PubMed

Publication Types