Display options
Share it on

Surg Case Rep. 2016 Dec;2(1):22. doi: 10.1186/s40792-016-0151-8. Epub 2016 Mar 10.

The development of large-cell carcinoma in the wall of a giant bulla complicated by hemorrhage.

Surgical case reports

Shota Nakamura, Koji Kawaguchi, Takayuki Fukui, Koichi Fukumoto, Toshiki Okasaka, Kohei Yokoi

Affiliations

  1. Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. [email protected].
  2. Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

PMID: 26964998 PMCID: PMC4786518 DOI: 10.1186/s40792-016-0151-8

Abstract

There were a few reports of patients with lung cancer developing at the wall of giant bullae complicated with hemorrhage. A 40-year-old male with complaints of hemoptysis was referred to our hospital, and a solitary pulmonary mass was pointed out on his chest roentgenogram. Computed tomography (CT) demonstrated a well-circumscribed solid mass measuring 7.0 × 6.5 × 6.0 cm in the right upper lobe of the lung. At the chest CT 1 year before, only a giant bulla without mass was found. From the interval change of CT findings with his clinical course, the mass was suspected as acute hemorrhage in the giant bulla. A right upper lobectomy of the lung was performed to control his hemoptysis. The surgical specimen showed the giant bulla filled with blood clot, and a partial wall of the bulla was irregularly thickened. Pathological examination revealed that the thickened wall was composed of large-cell carcinoma. In patients with bullous diseases complicated with hemorrhage, we should be aware of a possibility of developing lung cancer in the bullae.

Keywords: Bullae; Hemorrhage; Large-cell carcinoma

References

  1. Br J Haematol. 2008 Apr;141(1):1 - PubMed
  2. Kurume Med J. 2003;50(3-4):147-50 - PubMed
  3. Kyobu Geka. 2005 Aug;58(9):787-93 - PubMed
  4. Pneumonol Alergol Pol. 2012;80(3):275-9 - PubMed
  5. Surg Today. 1997;27(3):266-8 - PubMed
  6. Lung Cancer. 2002 Nov;38(2):185-91 - PubMed
  7. Nihon Kyobu Shikkan Gakkai Zasshi. 1995 Aug;33(8):906-10 - PubMed
  8. Intern Med. 2012;51(18):2673 - PubMed
  9. AJR Am J Roentgenol. 2003 Jun;180(6):1740 - PubMed

Publication Types