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Sex Transm Infect. 2016 Nov;92(7):487-491. doi: 10.1136/sextrans-2015-052475. Epub 2016 Mar 10.

A fruitful alliance: the synergy between .

Sexually transmitted infections

Liselotte Hardy, Vicky Jespers, Said Abdellati, Irith De Baetselier, Lambert Mwambarangwe, Viateur Musengamana, Janneke van de Wijgert, Mario Vaneechoutte, Tania Crucitti

Affiliations

  1. HIV and Sexual Health Group, Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
  2. Laboratory Bacteriology Research, Faculty of Medicine & Health Sciences, University of Ghent, Ghent, Belgium.
  3. STI Reference Laboratory, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
  4. Rinda Ubuzima, Kigali, Rwanda.
  5. Institute of Infection and Global Health, University of Liverpool, Liverpool, UK.

PMID: 26965870 PMCID: PMC5136707 DOI: 10.1136/sextrans-2015-052475

Abstract

OBJECTIVES: Bacterial vaginosis (BV) is characterised by a change in the microbial composition of the vagina. The BV-associated organisms outnumber the health-associated

METHODS: To this purpose, we evaluated the association between the presence of both bacteria by fluorescence in situ hybridisation (FISH) and BV by Nugent scoring in 463 vaginal slides of 120 participants participating in a clinical trial in Rwanda.

RESULTS: A bacterial biofilm was detected in half of the samples using a universal bacterial probe. The biofilm contained

CONCLUSIONS: Our study, although not comprehensive at studying the polymicrobial biofilm in BV, provided a strong indication towards the importance of

TRIAL REGISTRATION NUMBER: NCT01796613.

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Keywords: ANTIBIOTIC SENSITIVITY; BACTERIAL VAGINOSIS; DIAGNOSIS; GENITAL TRACT INFECT; MICROBIOLOGY

Conflict of interest statement

Competing interests: None declared.

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