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Kwon CI, Lehman GA. Mechanisms of Biliary Plastic Stent Occlusion and Efforts at Prevention. Clin Endosc. 2016;49(2):139-46doi: 10.5946/ce.2016.024.
Kwon, C. I., & Lehman, G. A. (2016). Mechanisms of Biliary Plastic Stent Occlusion and Efforts at Prevention. Clinical endoscopy, 49(2), 139-46. https://doi.org/10.5946/ce.2016.024
Kwon, Chang-Il, and Lehman, Glen A. "Mechanisms of Biliary Plastic Stent Occlusion and Efforts at Prevention." Clinical endoscopy vol. 49,2 (2016): 139-46. doi: https://doi.org/10.5946/ce.2016.024
Kwon CI, Lehman GA. Mechanisms of Biliary Plastic Stent Occlusion and Efforts at Prevention. Clin Endosc. 2016 Mar;49(2):139-46. doi: 10.5946/ce.2016.024. Epub 2016 Mar 22. PMID: 27000422; PMCID: PMC4821514.
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Clin Endosc. 2016 Mar;49(2):139-46. doi: 10.5946/ce.2016.024. Epub 2016 Mar 22.

Mechanisms of Biliary Plastic Stent Occlusion and Efforts at Prevention.

Clinical endoscopy

Chang-Il Kwon, Glen A Lehman

Affiliations

  1. Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
  2. Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA.

PMID: 27000422 PMCID: PMC4821514 DOI: 10.5946/ce.2016.024

Abstract

Biliary stenting via endoscopic retrograde cholangiopancreatography has greatly improved the quality of patient care over the last 30 years. Plastic stent occlusion limits the life span of such stents. Attempts to improve plastic stent patency duration have mostly failed. Metal stents (self-expandable metal stents [SEMSs]) have therefore replaced plastic stents, especially for malignant biliary strictures. SEMS are at least 10 times more expensive than plastic stents. In this focused review, we will discuss basic mechanisms of plastic stent occlusion, along with a systematic summary of previous efforts and related studies to improve stent patency and potential new techniques to overcome existing limitations.

Keywords: Biliary tract; Biofilms; Occlusion; Patency; Stents

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