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Imagama T, Tokushige A, Seki K, et al. Weight bearing joints destruction in rheumatoid arthritis. Curr Rheumatol Rev. 2016;
Imagama, T., Tokushige, A., Seki, K., & Taguchi, T. (2016). Weight bearing joints destruction in rheumatoid arthritis. Current rheumatology reviews, .
Imagama, Takashi, et al. "Weight bearing joints destruction in rheumatoid arthritis." Current rheumatology reviews vol. (2016).
Imagama T, Tokushige A, Seki K, Taguchi T. Weight bearing joints destruction in rheumatoid arthritis. Curr Rheumatol Rev. 2016 Mar 31; Epub 2016 Mar 31. PMID: 27030257.
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Curr Rheumatol Rev. 2016 Mar 31; Epub 2016 Mar 31.

Weight bearing joints destruction in rheumatoid arthritis.

Current rheumatology reviews

Takashi Imagama, Atsunori Tokushige, Kazushige Seki, Toshihiko Taguchi

Affiliations

  1. Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Minamikogushi1-1-1, Japan.

PMID: 27030257

Abstract

In many cases of rheumatoid arthritis (RA) joints of the upper extremities are affected. However, involvement of weight bearing joints of the lower extremities is strongly associated with a decreased activities of daily living ability such as gait disorder. Once the progression of weight bearing joint destruction occurs, lower extremity function will decrease even if RA disease activity is improved by pharmacotherapy. In this article, we investigated joint destruction-suppressing effects of pharmacotherapy on the hip and knee joints, as well as risk factors for joint destruction. We also discuss surgical treatment strategies and clinical outcomes for progressive joint destruction.

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