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Yamaguchi M, Fukuda T, Nakahara M, et al. Multicentric solid pseudopapillary neoplasms of the pancreas diagnosed by endoscopic ultrasound-guided fine needle aspiration: a case report. Surg Case Rep. 2015;1(1):110doi: 10.1186/s40792-015-0111-8.
Yamaguchi, M., Fukuda, T., Nakahara, M., Amano, M., Takei, D., Kawashima, M., Sumi, Y., Amano, H., Yonehara, S., Hanada, K., & Noriyuki, T. (2015). Multicentric solid pseudopapillary neoplasms of the pancreas diagnosed by endoscopic ultrasound-guided fine needle aspiration: a case report. Surgical case reports, 1(1), 110. https://doi.org/10.1186/s40792-015-0111-8
Yamaguchi, Megumi, et al. "Multicentric solid pseudopapillary neoplasms of the pancreas diagnosed by endoscopic ultrasound-guided fine needle aspiration: a case report." Surgical case reports vol. 1,1 (2015): 110. doi: https://doi.org/10.1186/s40792-015-0111-8
Yamaguchi M, Fukuda T, Nakahara M, Amano M, Takei D, Kawashima M, Sumi Y, Amano H, Yonehara S, Hanada K, Noriyuki T. Multicentric solid pseudopapillary neoplasms of the pancreas diagnosed by endoscopic ultrasound-guided fine needle aspiration: a case report. Surg Case Rep. 2015 Dec;1(1):110. doi: 10.1186/s40792-015-0111-8. Epub 2015 Oct 27. PMID: 26943434; PMCID: PMC4623871.
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Surg Case Rep. 2015 Dec;1(1):110. doi: 10.1186/s40792-015-0111-8. Epub 2015 Oct 27.

Multicentric solid pseudopapillary neoplasms of the pancreas diagnosed by endoscopic ultrasound-guided fine needle aspiration: a case report.

Surgical case reports

Megumi Yamaguchi, Toshikatsu Fukuda, Masahiro Nakahara, Mio Amano, Daisuke Takei, Masumi Kawashima, Yusuke Sumi, Hironobu Amano, Shuji Yonehara, Keiji Hanada, Toshio Noriyuki

Affiliations

  1. Department of Surgery, Onomichi General Hospital, 1-10-23, Hirahara, Onomichi, Hiroshima, 722-8508, Japan. [email protected].
  2. Department of Surgery, Onomichi General Hospital, 1-10-23, Hirahara, Onomichi, Hiroshima, 722-8508, Japan. [email protected].
  3. Department of Surgery, Onomichi General Hospital, 1-10-23, Hirahara, Onomichi, Hiroshima, 722-8508, Japan. [email protected].
  4. Department of Gastroenterology, Onomichi General Hospital, 1-10-23, Hirahara, Onomichi, Hiroshima, 722-8508, Japan. [email protected].
  5. Department of Surgery, Onomichi General Hospital, 1-10-23, Hirahara, Onomichi, Hiroshima, 722-8508, Japan. [email protected].
  6. Department of Surgery, Onomichi General Hospital, 1-10-23, Hirahara, Onomichi, Hiroshima, 722-8508, Japan. [email protected].
  7. Department of Surgery, Onomichi General Hospital, 1-10-23, Hirahara, Onomichi, Hiroshima, 722-8508, Japan. [email protected].
  8. Department of Surgery, Onomichi General Hospital, 1-10-23, Hirahara, Onomichi, Hiroshima, 722-8508, Japan. [email protected].
  9. Department of Diagnostic Pathology, Onomichi General Hospital, 1-10-23, Hirahara, Onomichi, Hiroshima, 722-8508, Japan. [email protected].
  10. Department of Gastroenterology, Onomichi General Hospital, 1-10-23, Hirahara, Onomichi, Hiroshima, 722-8508, Japan. [email protected].
  11. Faculty of Medicine, Hiroshima University, 1-2-3, Kasumi, Hiroshima, 734-8551, Japan. [email protected].

PMID: 26943434 PMCID: PMC4623871 DOI: 10.1186/s40792-015-0111-8

Abstract

Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor. This neoplasm usually arises as a single mass; multicentricity is exceptionally rare. We report the preoperative diagnosis of multicentric SPNs by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). A 32-year-old woman presented to the hospital with a pancreatic tumor that was detected on abdominal echography. Contrast-enhanced computed tomography (CT) scans revealed a 5-mm low-density mass in the body of the pancreas and a 10-mm mass in the tail of the pancreas. Magnetic resonance imaging (MRI) also revealed two tumors in the body and tail of the pancreas. On endoscopic ultrasonography (EUS), two indistinct and heterogeneous echogenic masses were found, and EUS-FNA was performed for each of these tumors. Cytological analysis revealed that the two masses were highly cellular with papillary groups of small, uniform, oval cells surrounding a fibrovascular core. Immunohistochemistry was positive for α-1 antitrypsin, vimentin, neuron-specific enolase (NSE), CD10, and progesterone receptor. These features confirmed the preoperative diagnosis of multicentric SPNs. The patient underwent laparoscopic distal pancreatectomy with splenectomy. The final pathologic diagnosis was multicentric SPNs. During 2 years of follow-up, she has not developed any recurrence.

Keywords: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA); Multicentric; Solid pseudopapillary neoplasm (SPN)

References

  1. Arch Pathol Lab Med. 1991 Sep;115(9):958-60 - PubMed
  2. J Gastroenterol. 1998 Jun;33(3):439-42 - PubMed
  3. Scott Med J. 2014 Aug;59(3):e8-e12 - PubMed
  4. Cancer Imaging. 2011 Nov 26;11:175-8 - PubMed
  5. World J Surg Oncol. 2013 May 23;11:106 - PubMed
  6. Dig Liver Dis. 2010 Jul;42(7):520-3 - PubMed
  7. Surg Endosc. 2014 Sep;28(9):2592-8 - PubMed
  8. J Natl Med Assoc. 2003 Dec;95(12):1204-7 - PubMed
  9. Med Oncol. 2013 Mar;30(1):330 - PubMed
  10. Intern Med. 2013;52(15):1703-8 - PubMed
  11. World J Gastroenterol. 2012 Oct 14;18(38):5329-37 - PubMed
  12. Korean J Pathol. 2012 Aug;46(4):399-406 - PubMed
  13. Clin J Gastroenterol. 2010 Dec;3(6):301-6 - PubMed
  14. Gastrointest Endosc. 2012 Feb;75(2):319-31 - PubMed

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