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Aoyagi K, Kizaki J, Isobe T, et al. Long-term survival of a patient with small cell carcinoma of the stomach with metachronous lung metastases treated by multimodal therapy: a case report. Surg Case Rep. 2015;1(1):125doi: 10.1186/s40792-015-0126-1.
Aoyagi, K., Kizaki, J., Isobe, T., & Akagi, Y. (2015). Long-term survival of a patient with small cell carcinoma of the stomach with metachronous lung metastases treated by multimodal therapy: a case report. Surgical case reports, 1(1), 125. https://doi.org/10.1186/s40792-015-0126-1
Aoyagi, Keishiro, et al. "Long-term survival of a patient with small cell carcinoma of the stomach with metachronous lung metastases treated by multimodal therapy: a case report." Surgical case reports vol. 1,1 (2015): 125. doi: https://doi.org/10.1186/s40792-015-0126-1
Aoyagi K, Kizaki J, Isobe T, Akagi Y. Long-term survival of a patient with small cell carcinoma of the stomach with metachronous lung metastases treated by multimodal therapy: a case report. Surg Case Rep. 2015 Dec;1(1):125. doi: 10.1186/s40792-015-0126-1. Epub 2015 Dec 24. PMID: 26943449; PMCID: PMC4690825.
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Surg Case Rep. 2015 Dec;1(1):125. doi: 10.1186/s40792-015-0126-1. Epub 2015 Dec 24.

Long-term survival of a patient with small cell carcinoma of the stomach with metachronous lung metastases treated by multimodal therapy: a case report.

Surgical case reports

Keishiro Aoyagi, Junya Kizaki, Taro Isobe, Yoshito Akagi

Affiliations

  1. Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan. [email protected].
  2. Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan. [email protected].
  3. Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan. [email protected].
  4. Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan. [email protected].

PMID: 26943449 PMCID: PMC4690825 DOI: 10.1186/s40792-015-0126-1

Abstract

A 69-year-old man was referred to our institution for treatment of gastric cancer. Type 2 gastric cancer was found on the anterior wall of the lower body of the stomach.The patient underwent distal gastrectomy, D2 lymph node dissection, and Roux-en-Y reconstruction with curative resection. The tumor was diagnosed as a small cell carcinoma of the stomach. Recurrence occurred in the lung after surgery. The patient underwent several chemoradiation therapy regimens, including cisplatin + irinotecan + radiation, S-1 + paclitaxel, amrubicin, carboplatin + etoposide, nogitecan, and docetaxel for lung metastases and radiation for brain and bone metastases for 43 months. He finally died of brain metastases 74 months after surgery (47 months after recognition of the lung metastases). Long continuous multimodal treatment including surgery, regimens for small cell lung cancer, S-1, taxanes, and radiation was thought to prolong the survival of this man with small cell carcinoma of the stomach.

Keywords: Long survival; Lung metastasis; Multimodal therapy; Small cell carcinoma; Stomach

References

  1. Gastric Cancer. 2011 Jun;14(2):113-23 - PubMed
  2. Gan To Kagaku Ryoho. 2006 Aug;33(8):1143-6 - PubMed
  3. Sci Rep. 2015 Apr 22;5:9444 - PubMed
  4. Fukuoka Igaku Zasshi. 1976 Feb;67(2):65-73 - PubMed
  5. Lancet Oncol. 2008 Mar;9(3):215-21 - PubMed
  6. Gastric Cancer. 2011 Jun;14(2):101-12 - PubMed
  7. Gan To Kagaku Ryoho. 1997 Dec;24(15):2277-80 - PubMed
  8. Horm Metab Res. 2011 Nov;43(12):832-7 - PubMed
  9. J Clin Oncol. 2006 Aug 1;24(22):3548-54 - PubMed
  10. Nihon Shokakibyo Gakkai Zasshi. 2013 Jan;110(1):56-63 - PubMed
  11. Lancet Oncol. 2009 Nov;10 (11):1063-9 - PubMed

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