Display options
Cite
Otsuka R, Kano M, Hayashi H, et al. Probable IgG4-related sclerosing disease presenting as a gastric submucosal tumor with an intense tracer uptake on PET/CT: a case report. Surg Case Rep. 2016;2(1):33doi: 10.1186/s40792-016-0161-6.
Otsuka, R., Kano, M., Hayashi, H., Hanari, N., Gunji, H., Hayano, K., & Matsubara, H. (2016). Probable IgG4-related sclerosing disease presenting as a gastric submucosal tumor with an intense tracer uptake on PET/CT: a case report. Surgical case reports, 2(1), 33. https://doi.org/10.1186/s40792-016-0161-6
Otsuka, Ryota, et al. "Probable IgG4-related sclerosing disease presenting as a gastric submucosal tumor with an intense tracer uptake on PET/CT: a case report." Surgical case reports vol. 2,1 (2016): 33. doi: https://doi.org/10.1186/s40792-016-0161-6
Otsuka R, Kano M, Hayashi H, Hanari N, Gunji H, Hayano K, Matsubara H. Probable IgG4-related sclerosing disease presenting as a gastric submucosal tumor with an intense tracer uptake on PET/CT: a case report. Surg Case Rep. 2016 Dec;2(1):33. doi: 10.1186/s40792-016-0161-6. Epub 2016 Apr 08. PMID: 27059471; PMCID: PMC4826359.
Copy Download .nbib Format: NLM
Share it on

Surg Case Rep. 2016 Dec;2(1):33. doi: 10.1186/s40792-016-0161-6. Epub 2016 Apr 08.

Probable IgG4-related sclerosing disease presenting as a gastric submucosal tumor with an intense tracer uptake on PET/CT: a case report.

Surgical case reports

Ryota Otsuka, Masayuki Kano, Hideki Hayashi, Naoyuki Hanari, Hisashi Gunji, Koichi Hayano, Hisahiro Matsubara

Affiliations

  1. Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1-8-1, Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan. [email protected].
  2. Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1-8-1, Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.

PMID: 27059471 PMCID: PMC4826359 DOI: 10.1186/s40792-016-0161-6

Abstract

A 44-year-old man consulted an internist because of abnormalities in an upper gastrointestinal series. It showed an elevated lesion with central depression in the greater curvature of the middle part of the stomach. Upper gastrointestinal endoscopy showed an elevated lesion with central depression, bridging hold, and no abnormalities of the gastric mucosa in the greater curvature of the middle part of the stomach. Endoscopic ultrasonography showed a submucosal tumor derived from the muscle layer of the stomach. Computed tomography showed a 22-mm tumor in the upper part of the stomach. Integrated position emission tomography/computed tomography (PET/CT) showed an intense tracer uptake by the tumor. Based on these findings, a gastrointestinal stromal tumor was suspected and laparoscopic endoscopic cooperative surgery was performed. A histopathological examination showed lymphoplasmacytic infiltration and fibrosis, and an immunohistochemical analysis showed the infiltration of IgG4-positive lymphoplasmacytic cells. The probable diagnosis was IgG4-related sclerosing disease of the stomach. We herein describe a rare case of probable IgG4-related sclerosing disease which presented as a gastric submucosal tumor. PET/CT is a useful imaging technique for the diagnosis and follow-up of this disease.

Keywords: Gastric submucosal tumor; IgG4-related sclerosing disease; Laparoscopic endoscopic cooperative surgery; Position emission tomography/computed tomography

References

  1. ISRN Gastroenterol. 2011;2011:873087 - PubMed
  2. JOP. 2011 May 06;12(3):297-305 - PubMed
  3. Am J Surg Pathol. 2004 Sep;28(9):1193-203 - PubMed
  4. World J Gastroenterol. 2008 Jul 7;14(25):3948-55 - PubMed
  5. World J Gastroenterol. 2010 May 7;16(17):2183-6 - PubMed
  6. J Gastroenterol. 2003;38(10):982-4 - PubMed
  7. Nihon Naika Gakkai Zasshi. 2012 Feb 10;101(2):468-71 - PubMed
  8. Mod Rheumatol. 2012 Feb;22(1):21-30 - PubMed

Publication Types