Display options
Share it on

Addict Disord Their Treat. 2016 Mar;15(1):1-5. doi: 10.1097/ADT.0000000000000059.

Everyday problems with executive dysfunction and impulsivity in adults recovering from methamphetamine addiction.

Addictive disorders & their treatment

Carilyn Ellis, William Hoffman, Sarah Jaehnert, Jane Plagge, Jennifer M Loftis, Daniel Schwartz, Marilyn Huckans

Affiliations

  1. Research and Development Service, Portland VA Medical Center, Portland, Oregon; Behavioral Health & Clinical Neurosciences Division, Portland VA Medical Center, Portland, Oregon; Methamphetamine Abuse Research Center, Oregon Health & Science University, Portland, Oregon; Doctor of Psychology Program, George Fox University, Newberg, Oregon.
  2. Research and Development Service, Portland VA Medical Center, Portland, Oregon; Behavioral Health & Clinical Neurosciences Division, Portland VA Medical Center, Portland, Oregon; Department of Psychiatry, School of Medicine, Oregon Health & Science University, Portland, Oregon; Methamphetamine Abuse Research Center, Oregon Health & Science University, Portland, Oregon; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland OR.
  3. Research and Development Service, Portland VA Medical Center, Portland, Oregon; Behavioral Health & Clinical Neurosciences Division, Portland VA Medical Center, Portland, Oregon; Methamphetamine Abuse Research Center, Oregon Health & Science University, Portland, Oregon; School of Professional Psychology, Pacific University, Hillsboro, Oregon.
  4. Behavioral Health & Clinical Neurosciences Division, Portland VA Medical Center, Portland, Oregon.
  5. Research and Development Service, Portland VA Medical Center, Portland, Oregon; Department of Psychiatry, School of Medicine, Oregon Health & Science University, Portland, Oregon; Methamphetamine Abuse Research Center, Oregon Health & Science University, Portland, Oregon.
  6. Research and Development Service, Portland VA Medical Center, Portland, Oregon; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland OR; Behavioral Health & Clinical Neurosciences Division, Portland VA Medical Center, Portland, Oregon; Department of Psychiatry, School of Medicine, Oregon Health & Science University, Portland, Oregon; Methamphetamine Abuse Research Center, Oregon Health & Science University, Portland, Oregon.

PMID: 27034621 PMCID: PMC4809534 DOI: 10.1097/ADT.0000000000000059

Abstract

OBJECTIVES: Compared with non-addicted controls (CTLs), adults in remission from methamphetamine addiction (MA-REM) evidence impairments on objective measures of executive functioning and impulsivity.

METHODS: To evaluate the impact of these impairments in MA-REM adults, demographically matched groups (MA-REM, n=30; CTLs, n=24) completed objective and self-report measures of executive functioning and impulsivity.

RESULTS: MA-REM adults demonstrated significantly (p < 0.050) greater objective and subjective problems with executive functioning and impulsivity.

CONCLUSIONS: These results suggest that adults in MA-REM are aware of their deficits and that these deficits have significant impact in everyday life.

Keywords: Executive Function; Impulsivity; Methamphetamine

References

  1. J Psychoactive Drugs. 2003 May;35 Suppl 1:161-8 - PubMed
  2. Psychopharmacology (Berl). 2006 Oct;188(2):162-70 - PubMed
  3. Drug Alcohol Rev. 2008 May;27(3):253-62 - PubMed
  4. Subst Abuse Treat Prev Policy. 2008 Jul 25;3:19 - PubMed
  5. Arch Gen Psychiatry. 2006 Jan;63(1):90-100 - PubMed
  6. J Subst Abuse Treat. 2005 Sep;29(2):85-93 - PubMed
  7. Neurosci Biobehav Rev. 2011 Jan;35(3):377-406 - PubMed
  8. Addiction. 2007 Apr;102 Suppl 1:16-32 - PubMed
  9. J Clin Exp Neuropsychol. 2007 Feb;29(2):155-9 - PubMed
  10. Neuropsychol Rev. 2007 Sep;17(3):275-97 - PubMed
  11. Drug Alcohol Depend. 2012 Sep 1;125(1-2):146-53 - PubMed
  12. J Stud Alcohol Drugs. 2012 Jul;73(4):625-34 - PubMed
  13. J Neuropsychiatry Clin Neurosci. 2003 Summer;15(3):317-25 - PubMed
  14. Arch Gen Psychiatry. 2004 Jan;61(1):73-84 - PubMed
  15. Neurotox Res. 2011 Jul;20(1):59-68 - PubMed
  16. Drug Alcohol Rev. 2010 Jan;29(1):12-20 - PubMed
  17. Addiction. 2006 Oct;101(10):1473-8 - PubMed
  18. J Clin Psychol. 1995 Nov;51(6):768-74 - PubMed
  19. Addiction. 2005 Sep;100(9):1320-9 - PubMed
  20. J Neuropsychiatry Clin Neurosci. 2012 Summer;24(3):331-9 - PubMed
  21. Neuroimage. 2010 May 1;50(4):1392-401 - PubMed
  22. Subst Use Misuse. 2011;46(1):23-34 - PubMed
  23. Drug Alcohol Depend. 2008 Apr 1;94(1-3):82-91 - PubMed
  24. Psychol Sci. 2011 Jul;22(7):968-75 - PubMed
  25. Psychopharmacology (Berl). 2008 Dec;201(2):183-93 - PubMed
  26. Ann N Y Acad Sci. 2008 Oct;1141:195-220 - PubMed
  27. Biol Psychiatry. 2003 Jan 1;53(1):65-74 - PubMed
  28. Am J Addict. 2004 Mar-Apr;13(2):181-90 - PubMed
  29. Drug Alcohol Depend. 2005 Aug 1;79(2):273-7 - PubMed

Publication Types

Grant support