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J Ophthalmol. 2016;2016:5465272. doi: 10.1155/2016/5465272. Epub 2016 Feb 29.

A Controlled Study on the Correlation between Tear Film Volume and Tear Film Stability in Diabetic Patients.

Journal of ophthalmology

Iman M Eissa, Noha M Khalil, Heba A El-Gendy

Affiliations

  1. Department of Ophthalmology, Cairo University, Cairo 11562, Egypt.

PMID: 27034823 PMCID: PMC4789474 DOI: 10.1155/2016/5465272

Abstract

Purpose. To assess the tear film quantity and correlate it with the quality and stability of the tear film in diabetics and compare them to age matched controls. Introduction. Diabetes affects tear film parameters in multiple ways. Poor metabolic control and neuropathy are postulated factors. To further understand how diabetes affects tear film parameters this study was conducted. Subjects and Methods. Tear meniscus height was measured by anterior segment OCT, along with tear thinning time, a subtype of noninvasive tear break-up time, and blinking rate per minute which were all recorded for 22 diabetic patients. Correlations between these tear film parameters were studied and then compared to 16 age matched controls. Results. A statistically significant difference was found in blinking rate between the diabetic and the control group (P = 0.002), with higher blinking rate among diabetics. All tear film parameters were negatively correlated with duration of diabetes. A positive correlation was found between tear film volume and stability. Conclusion. Diabetes affects the tear film in various ways. Diabetics should be examined for dry eye signs even in absence of symptoms which may be masked by associated neuropathy. Duration of diabetes has an impact on tear film status.

References

  1. Acta Ophthalmol. 2014 Mar;92(2):e96-e104 - PubMed
  2. Invest Ophthalmol Vis Sci. 2003 Oct;44(10):4223-9 - PubMed
  3. BMC Ophthalmol. 2008 Jun 02;8:10 - PubMed
  4. Arch Soc Esp Oftalmol. 2011 Apr;86(4):107-12 - PubMed
  5. Curr Opin Rheumatol. 1995 Sep;7(5):409-16 - PubMed
  6. Mov Disord. 1997 Nov;12(6):1028-34 - PubMed
  7. Am J Ophthalmol. 2004 Sep;138(3):381-8 - PubMed
  8. Diabetes Res Clin Pract. 2003 Mar;59(3):195-9 - PubMed
  9. JAMA. 2013 Nov 27;310(20):2191-4 - PubMed
  10. Cornea. 2003 Jan;22(1):15-8 - PubMed
  11. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5060-5 - PubMed
  12. J Diabetes Res. 2014;2014:848659 - PubMed
  13. Ophthalmology. 2003 Jun;110(6):1102-9 - PubMed
  14. Invest Ophthalmol Vis Sci. 2004 May;45(5):1369-74 - PubMed
  15. Eye (Lond). 2005 Apr;19(4):418-21 - PubMed
  16. Optom Vis Sci. 2009 Feb;86(2):E106-14 - PubMed
  17. Korean J Ophthalmol. 2004 Dec;18(2):168-74 - PubMed
  18. Ophthalmologica. 2008;222(4):284-91 - PubMed

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