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Alnasrallah B, Collins JF, Zwi LJ. Bile Nephropathy in Flucloxacillin-Induced Cholestatic Liver Dysfunction. Case Rep Nephrol. 2016;2016:4162674doi: 10.1155/2016/4162674.
Alnasrallah, B., Collins, J. F., & Zwi, L. J. (2016). Bile Nephropathy in Flucloxacillin-Induced Cholestatic Liver Dysfunction. Case reports in nephrology, 20164162674. https://doi.org/10.1155/2016/4162674
Alnasrallah, Basil, et al. "Bile Nephropathy in Flucloxacillin-Induced Cholestatic Liver Dysfunction." Case reports in nephrology vol. 2016 (2016): 4162674. doi: https://doi.org/10.1155/2016/4162674
Alnasrallah B, Collins JF, Zwi LJ. Bile Nephropathy in Flucloxacillin-Induced Cholestatic Liver Dysfunction. Case Rep Nephrol. 2016;2016:4162674. doi: 10.1155/2016/4162674. Epub 2016 Feb 24. PMID: 27006842; PMCID: PMC4783551.
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Case Rep Nephrol. 2016;2016:4162674. doi: 10.1155/2016/4162674. Epub 2016 Feb 24.

Bile Nephropathy in Flucloxacillin-Induced Cholestatic Liver Dysfunction.

Case reports in nephrology

Basil Alnasrallah, John F Collins, L Jonathan Zwi

Affiliations

  1. Department of Nephrology, Auckland City Hospital, Auckland 1023, New Zealand.
  2. Department of Pathology, Auckland City Hospital, Auckland 1023, New Zealand.

PMID: 27006842 PMCID: PMC4783551 DOI: 10.1155/2016/4162674

Abstract

Kidney injury in the context of cholestatic liver dysfunction is not uncommon; this has been historically referred to as cholemic nephrosis implying a direct deleterious renal effect of cholemia. However, scepticism about the exact role that bile and its constituents play in this injury has led to the disappearance of the term. We describe a case of severe AKI due to bile nephropathy with bile casts in flucloxacillin-induced liver dysfunction. We also discuss the recent literature reviving the concept of bile nephropathy.

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