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Calvo-Maroto AM, Esteve-Taboada JJ, Pérez-Cambrodí RJ, et al. Pilot Study on Visual Function and Fundus Autofluorescence Assessment in Diabetic Patients. J Ophthalmol. 2016;2016:1287847doi: 10.1155/2016/1287847.
Calvo-Maroto, A. M., Esteve-Taboada, J. J., Pérez-Cambrodí, R. J., Madrid-Costa, D., & Cerviño, A. (2016). Pilot Study on Visual Function and Fundus Autofluorescence Assessment in Diabetic Patients. Journal of ophthalmology, 20161287847. https://doi.org/10.1155/2016/1287847
Calvo-Maroto, Ana M, et al. "Pilot Study on Visual Function and Fundus Autofluorescence Assessment in Diabetic Patients." Journal of ophthalmology vol. 2016 (2016): 1287847. doi: https://doi.org/10.1155/2016/1287847
Calvo-Maroto AM, Esteve-Taboada JJ, Pérez-Cambrodí RJ, Madrid-Costa D, Cerviño A. Pilot Study on Visual Function and Fundus Autofluorescence Assessment in Diabetic Patients. J Ophthalmol. 2016;2016:1287847. doi: 10.1155/2016/1287847. Epub 2016 Feb 10. PMID: 26977312; PMCID: PMC4764742.
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J Ophthalmol. 2016;2016:1287847. doi: 10.1155/2016/1287847. Epub 2016 Feb 10.

Pilot Study on Visual Function and Fundus Autofluorescence Assessment in Diabetic Patients.

Journal of ophthalmology

Ana M Calvo-Maroto, José J Esteve-Taboada, Rafael J Pérez-Cambrodí, David Madrid-Costa, Alejandro Cerviño

Affiliations

  1. Optometry Research Group, Department of Optics & Optometry & Vision Sciences, University of Valencia, Burjassot, 46100 Valencia, Spain.
  2. Department of Ophthalmology, Oftalmar, Medimar International Hospital, 03016 Alicante, Spain.

PMID: 26977312 PMCID: PMC4764742 DOI: 10.1155/2016/1287847

Abstract

Purpose. Evaluate optimized fundus autofluorescence (FAF) imaging in early stages of diabetic retinopathy (DR) and relate findings with conventional colour fundus imaging and visual function in diabetic patients and control subjects. Materials and Methods. FAF and colour images were obtained using the CR-2 Plus digital nonmydriatic retinal camera in seven diabetic patients and thirteen control subjects. Visual-Functioning Questionnaire-25 (VFQ-25) and Diabetes Self-Management Questionnaire (DSMQ) were used to assess the quality of life and diabetes self-care. Contrast sensitivity function (CSF) was evaluated with the Vistech 6500 chart. Results. FAF and optimized-FAF imaging showed more retinal alterations related to DR than colour imaging. In diabetic patients, compatible signs with microaneurysms, capillary dilations, and haemorrhages were less numerous in colour imaging than optimized-FAF and FAF imaging in areas analysed. Control subjects at risk of developing DM showed more retinal pigment epithelium defects than those without risk in all retinal areas. Significant differences were not found in VFQ-25 and CSF between diabetic patients and control subjects. Conclusions. FAF and optimized-FAF imaging showed significant alterations related to DR not observed in colour imaging. FAF and optimized-FAF images could be a useful complementary tool for detecting early alterations associated with the development and progression of DR.

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