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Data Brief. 2015 Dec 31;6:461-5. doi: 10.1016/j.dib.2015.12.028. eCollection 2016 Mar.

Data in support of the negative influence of divalent cations on (-)-epigallocatechin-3-gallate (EGCG)-mediated inhibition of matrix metalloproteinase-2 (MMP-2).

Data in brief

Gauri Deb, Sahil Batra, Anil M Limaye

Affiliations

  1. Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India.

PMID: 26977427 PMCID: PMC4773573 DOI: 10.1016/j.dib.2015.12.028

Abstract

In this data article we have provided evidence for the negative influence of divalent cations on (-)-epigallocatechin-3-gallate (EGCG)-mediated inhibition of matrix metalloproteinase-2 (MMP-2) activity in cell-free experiments. Chelating agents, such as EDTA and sodium citrate alone, did not affect MMP-2 activity. While EDTA enhanced, excess of divalent cations interfered with EGCG-mediated inhibition of MMP-2.

References

  1. Mol Cell Endocrinol. 2008 Nov 6;294(1-2):10-8 - PubMed
  2. Nat Methods. 2012 Jul;9(7):671-5 - PubMed

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