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English JA, Scaife C, Harauma A, et al. Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation. Data Brief. 2016;7:341-3doi: 10.1016/j.dib.2015.12.057.
English, J. A., Scaife, C., Harauma, A., Focking, M., Wynne, K., Cagney, G., Moriguchi, T., & Cotter, D. R. (2016). Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation. Data in brief, 7341-3. https://doi.org/10.1016/j.dib.2015.12.057
English, Jane A, et al. "Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation." Data in brief vol. 7 (2016): 341-3. doi: https://doi.org/10.1016/j.dib.2015.12.057
English JA, Scaife C, Harauma A, Focking M, Wynne K, Cagney G, Moriguchi T, Cotter DR. Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation. Data Brief. 2016 Feb 15;7:341-3. doi: 10.1016/j.dib.2015.12.057. eCollection 2016 Jun. PMID: 26977433; PMCID: PMC4781930.
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Data Brief. 2016 Feb 15;7:341-3. doi: 10.1016/j.dib.2015.12.057. eCollection 2016 Jun.

Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation.

Data in brief

Jane A English, Caitriona Scaife, Akiko Harauma, Melanie Focking, Kieran Wynne, Gerard Cagney, Toru Moriguchi, David R Cotter

Affiliations

  1. Department of Psychiatry, Royal College of Surgeons in Ireland, ERC Beaumont Hospital, Dublin, Ireland; Proteome Research Centre, School of Medicine and Medical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland.
  2. Proteome Research Centre, School of Medicine and Medical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland.
  3. Department of Food and Life Science, Azabu University, Sagamihara, Japan.
  4. Department of Psychiatry, Royal College of Surgeons in Ireland, ERC Beaumont Hospital, Dublin, Ireland.

PMID: 26977433 PMCID: PMC4781930 DOI: 10.1016/j.dib.2015.12.057

Abstract

This dataset reports on the analysis of mouse hippocampus by LC-MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article "Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus" (English et al., 2013 [1]), in which a more comprehensive interpretation and analysis of the data is given.

Keywords: Brain; Hippocampus; Mass spectrometry; Mouse; Omega-3 deficiency; Proteins; Proteomics

References

  1. Front Genet. 2013 Oct 28;4:208 - PubMed

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