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Fiore LD, Brophy MT, Turek S, et al. The VA Point-of-Care Precision Oncology Program: Balancing Access with Rapid Learning in Molecular Cancer Medicine. Biomark Cancer. 2016;8:9-16doi: 10.4137/BIC.S37548.
Fiore, L. D., Brophy, M. T., Turek, S., Kudesia, V., Ramnath, N., Shannon, C., Ferguson, R., Pyarajan, S., Fiore, M. A., Hornberger, J., & Lavori, P. (2016). The VA Point-of-Care Precision Oncology Program: Balancing Access with Rapid Learning in Molecular Cancer Medicine. Biomarkers in cancer, 89-16. https://doi.org/10.4137/BIC.S37548
Fiore, Louis D, et al. "The VA Point-of-Care Precision Oncology Program: Balancing Access with Rapid Learning in Molecular Cancer Medicine." Biomarkers in cancer vol. 8 (2016): 9-16. doi: https://doi.org/10.4137/BIC.S37548
Fiore LD, Brophy MT, Turek S, Kudesia V, Ramnath N, Shannon C, Ferguson R, Pyarajan S, Fiore MA, Hornberger J, Lavori P. The VA Point-of-Care Precision Oncology Program: Balancing Access with Rapid Learning in Molecular Cancer Medicine. Biomark Cancer. 2016 Feb 29;8:9-16. doi: 10.4137/BIC.S37548. eCollection 2016. PMID: 26949343; PMCID: PMC4772906.
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Biomark Cancer. 2016 Feb 29;8:9-16. doi: 10.4137/BIC.S37548. eCollection 2016.

The VA Point-of-Care Precision Oncology Program: Balancing Access with Rapid Learning in Molecular Cancer Medicine.

Biomarkers in cancer

Louis D Fiore, Mary T Brophy, Sara Turek, Valmeek Kudesia, Nithya Ramnath, Colleen Shannon, Ryan Ferguson, Saiju Pyarajan, Melissa A Fiore, John Hornberger, Philip Lavori

Affiliations

  1. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), Veterans Affairs Boston Healthcare System, Department of Veterans Affairs Office of Research and Development-Cooperative Studies Program, Washington DC, USA.
  2. VA Ann Arbor Healthcare System, the University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA.
  3. Cedar Associates, Menlo Park, CA, USA.; Department of Health Research and Policy, Stanford University, Stanford, CA, USA.; Department of Medicine, Stanford University, Stanford, CA, USA.
  4. Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.; Department of Statistics, Stanford University, Stanford, CA, USA.

PMID: 26949343 PMCID: PMC4772906 DOI: 10.4137/BIC.S37548

Abstract

The Department of Veterans Affairs (VA) recognized the need to balance patient-centered care with responsible creation of generalizable knowledge on the effectiveness of molecular medicine tools. Embracing the principles of the rapid learning health-care system, a new clinical program called the Precision Oncology Program (POP) was created in New England. The POP integrates generalized knowledge about molecular medicine in cancer with a database of observations from previously treated veterans. The program assures access to modern genomic oncology practice in the veterans affairs (VA), removes disparities of access across the VA network of clinical centers, disseminates the products of learning that are generalizable to non-VA settings, and systematically presents opportunities for patients to participate in clinical trials of targeted therapeutics.

Keywords: Bayesian; learning health-care system; lung cancer; precision oncology; veterans

References

  1. J Am Med Inform Assoc. 2012 Jun;19(e1):e170-6 - PubMed
  2. Clin Nurse Spec. 2013 Jan-Feb;27(1):7-9 - PubMed
  3. Qual Health Res. 2014 Jan;24(1):46-54 - PubMed
  4. JAMA. 2011 Nov 2;306(17):1914-5 - PubMed
  5. J Clin Oncol. 2013 May 20;31(15):1803-5 - PubMed
  6. Clin Trials. 2011 Apr;8(2):183-95 - PubMed
  7. J Cancer Educ. 2013 Jun;28(2):237-46 - PubMed
  8. N Engl J Med. 2015 Feb 26;372(9):793-5 - PubMed
  9. Cell. 2014 Mar 27;157(1):241-53 - PubMed
  10. J Clin Oncol. 2015 Mar 20;33(9):1000-7 - PubMed
  11. Nat Rev Clin Oncol. 2014 Feb;11(2):109-18 - PubMed
  12. JAMA. 2014 May 21;311(19):1975-6 - PubMed
  13. JAMA. 2014 May 21;311(19):1998-2006 - PubMed
  14. Genet Test Mol Biomarkers. 2013 Jul;17(7):515-23 - PubMed
  15. J Clin Oncol. 2015 Mar 20;33(9):975-7 - PubMed
  16. J Clin Oncol. 2011 May 20;29(15):2121-7 - PubMed
  17. Health Aff (Millwood). 2014 Jul;33(7):1229-35 - PubMed
  18. N Engl J Med. 2015 Nov 19;373(21):2005-14 - PubMed

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