Display options
Cite
Crespo Yanguas S, Willebrords J, Maes M, et al. Connexins and pannexins in liver damage. EXCLI J. 2016;15:177-86doi: 10.17179/excli2016-119.
Crespo Yanguas, S., Willebrords, J., Maes, M., da Silva, T. C., Veloso Alves Pereira, I., Cogliati, B., Zaidan Dagli, M. L., & Vinken, M. (2016). Connexins and pannexins in liver damage. EXCLI journal, 15177-86. https://doi.org/10.17179/excli2016-119
Crespo Yanguas, Sara, et al. "Connexins and pannexins in liver damage." EXCLI journal vol. 15 (2016): 177-86. doi: https://doi.org/10.17179/excli2016-119
Crespo Yanguas S, Willebrords J, Maes M, da Silva TC, Veloso Alves Pereira I, Cogliati B, Zaidan Dagli ML, Vinken M. Connexins and pannexins in liver damage. EXCLI J. 2016 Feb 25;15:177-86. doi: 10.17179/excli2016-119. eCollection 2016. PMID: 27065778; PMCID: PMC4822047.
Copy Download .nbib Format: NLM
Share it on

EXCLI J. 2016 Feb 25;15:177-86. doi: 10.17179/excli2016-119. eCollection 2016.

Connexins and pannexins in liver damage.

EXCLI journal

Sara Crespo Yanguas, Joost Willebrords, Michaël Maes, Tereza Cristina da Silva, Isabel Veloso Alves Pereira, Bruno Cogliati, Maria Lucia Zaidan Dagli, Mathieu Vinken

Affiliations

  1. Department of In Vitro Toxicology and Dermato-Cosmetology, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.
  2. Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, Av. Prof. Dr. Orlando Marques de Paiva 87, São Paulo SP CEP 05508-900, Brazil.

PMID: 27065778 PMCID: PMC4822047 DOI: 10.17179/excli2016-119

Abstract

Connexins and pannexins are key players in the control of cellular communication and thus in the maintenance of tissue homeostasis. Inherent to this function these proteins are frequently involved in pathological processes. The present paper reviews the role of connexins and pannexins in liver toxicity and disease. As they act both as sensors and effectors in these deleterious events connexins and pannexins could represent a set of novel clinical diagnostic biomarkers and drug targets.

Keywords: acute liver injury; cholestasis; connexin; fibrosis; hepatitis; liver cancer; pannexin; steatosis

References

  1. Am J Physiol. 1999 May;276(5 Pt 2):R1249-57 - PubMed
  2. Arch Toxicol. 1999 Sep;73(7):373-80 - PubMed
  3. Cell Tissue Res. 2000 Apr;300(1):111-7 - PubMed
  4. Liver. 2000 Apr;20(2):104-7 - PubMed
  5. Curr Biol. 2000 Jun 29;10(13):R473-4 - PubMed
  6. Toxicol Pathol. 2000 Jul-Aug;28(4):540-7 - PubMed
  7. Am J Physiol Heart Circ Physiol. 2001 Jun;280(6):H2441-50 - PubMed
  8. Carcinogenesis. 2001 Oct;22(10):1593-600 - PubMed
  9. Am J Physiol Gastrointest Liver Physiol. 2002 Jun;282(6):G991-G1001 - PubMed
  10. Hepatology. 2002 Sep;36(3):631-40 - PubMed
  11. Biochem Biophys Res Commun. 2003 Jul 18;307(1):80-5 - PubMed
  12. Curr Med Chem. 2003 Oct;10(19):2045-58 - PubMed
  13. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13644-9 - PubMed
  14. Cell Commun Adhes. 2003 Jul-Dec;10(4-6):437-43 - PubMed
  15. Carcinogenesis. 2004 Apr;25(4):483-92 - PubMed
  16. Hepatology. 2004 Jul;40(1):205-10 - PubMed
  17. Biochem Biophys Res Commun. 2004 Sep 24;322(3):718-26 - PubMed
  18. J Gastroenterol. 2004 Aug;39(8):763-8 - PubMed
  19. Exp Cell Res. 2004 Oct 1;299(2):427-41 - PubMed
  20. Gastroenterology. 2005 Feb;128(2):433-48 - PubMed
  21. Biochim Biophys Acta. 2005 Dec 20;1719(1-2):125-45 - PubMed
  22. Cell Tissue Res. 2006 Jun;324(3):547-52 - PubMed
  23. EMBO J. 2006 Nov 1;25(21):5071-82 - PubMed
  24. J Biol Chem. 2007 Jan 26;282(4):2386-94 - PubMed
  25. Cancer Lett. 2007 Jul 18;252(2):208-15 - PubMed
  26. Life Sci. 2007 Mar 6;80(13):1228-35 - PubMed
  27. Mol Carcinog. 2007 Apr;46(4):269-74 - PubMed
  28. Int J Cancer. 2007 Aug 1;121(3):536-46 - PubMed
  29. Cancer Sci. 2007 Sep;98(9):1318-22 - PubMed
  30. J Membr Biol. 2007 Jun;217(1-3):53-61 - PubMed
  31. Cell Immunol. 2007 Jun;247(2):103-10 - PubMed
  32. J Cell Biochem. 2008 Jun 1;104(3):965-84 - PubMed
  33. Gastroenterology. 2008 May;134(6):1655-69 - PubMed
  34. J Immunol. 2008 Jun 1;180(11):7147-57 - PubMed
  35. Cell Death Differ. 2009 Apr;16(4):524-36 - PubMed
  36. Cell Commun Signal. 2009 Mar 12;7:4 - PubMed
  37. Crit Rev Biochem Mol Biol. 2009 Jul-Aug;44(4):201-22 - PubMed
  38. Cell Mol Life Sci. 2010 Mar;67(6):907-18 - PubMed
  39. Toxicol Pathol. 2010 Feb;38(2):280-6 - PubMed
  40. Nat Rev Gastroenterol Hepatol. 2010 Aug;7(8):425-36 - PubMed
  41. Microsc Res Tech. 2011 May;74(5):421-9 - PubMed
  42. Curr Med Chem. 2010;17(34):4191-230 - PubMed
  43. J Neurosci. 2011 Mar 30;31(13):4962-77 - PubMed
  44. Hepatology. 2011 Jul;54(1):133-44 - PubMed
  45. Mol Carcinog. 1990;3(5):273-8 - PubMed
  46. Toxicol Sci. 2012 Jan;125(1):175-86 - PubMed
  47. World J Gastroenterol. 2011 Nov 21;17(43):4772-8 - PubMed
  48. Nat Biotechnol. 2012 Jan 15;30(2):179-83 - PubMed
  49. Cancer Sci. 2012 May;103(5):860-7 - PubMed
  50. Cell Biochem Funct. 2012 Mar;30(2):89-100 - PubMed
  51. Nat Med. 2012 Mar 18;18(4):600-4 - PubMed
  52. Am J Physiol Cell Physiol. 2012 Nov 15;303(10):C1034-44 - PubMed
  53. J Vet Med Sci. 2013 Feb;75(2):207-10 - PubMed
  54. Basic Res Cardiol. 2013 Jan;108(1):309 - PubMed
  55. J Hepatol. 2013 Jun;58(6):1194-200 - PubMed
  56. J Proteome Res. 2013 Jun 7;12(6):2597-610 - PubMed
  57. Neurogastroenterol Motil. 2013 Jun;25(6):e395-405 - PubMed
  58. Neuropharmacology. 2013 Dec;75:491-505 - PubMed
  59. Curr Med Chem. 2013;20(24):3011-21 - PubMed
  60. BMC Cancer. 2013 Jun 24;13:306 - PubMed
  61. Nat Rev Gastroenterol Hepatol. 2013 Nov;10(11):686-90 - PubMed
  62. Exp Toxicol Pathol. 2014 Mar;66(2-3):103-10 - PubMed
  63. Liver Int. 2014 Jul;34(6):859-68 - PubMed
  64. Biochem J. 2014 Feb 15;458(1):1-10 - PubMed
  65. J Mol Med (Berl). 2014 Oct;92(10):1069-82 - PubMed
  66. Sci Rep. 2014 Jun 04;4:5169 - PubMed
  67. Mediators Inflamm. 2014;2014:742734 - PubMed
  68. Front Physiol. 2014 Sep 12;5:348 - PubMed
  69. FEBS J. 2015 Jan;282(2):259-70 - PubMed
  70. Front Cell Neurosci. 2014 Oct 21;8:306 - PubMed
  71. Front Cell Neurosci. 2014 Nov 25;8:392 - PubMed
  72. J Cell Biol. 1989 Dec;109(6 Pt 2):3391-401 - PubMed
  73. Gut. 2015 May;64(5):830-41 - PubMed
  74. Arch Toxicol. 2016 May;90(5):1025-1048 - PubMed
  75. Prog Lipid Res. 2015 Jul;59:106-25 - PubMed
  76. Biochim Biophys Acta. 2016 Jun;1862(6):1111-21 - PubMed
  77. Nature. 1987 Oct 22-28;329(6141):732-4 - PubMed
  78. J Cell Biol. 1986 Sep;103(3):767-76 - PubMed
  79. J Cell Biol. 1986 Jul;103(1):123-34 - PubMed
  80. Science. 1987 May 22;236(4804):967-9 - PubMed
  81. J Hepatol. 1995 May;22(5):536-9 - PubMed
  82. Am J Physiol. 1995 May;268(5 Pt 1):C1186-94 - PubMed
  83. Am J Pathol. 1995 Jun;146(6):1508-20 - PubMed
  84. Virchows Arch. 1994;425(4):407-12 - PubMed
  85. Cancer Res. 1994 Jun 15;54(12):3145-52 - PubMed
  86. Int J Cancer. 1994 Jan 2;56(1):87-94 - PubMed
  87. J Histochem Cytochem. 1993 Jul;41(7):971-80 - PubMed
  88. J Hepatol. 1996 Oct;25(4):529-37 - PubMed
  89. Cell Tissue Res. 1998 Nov;294(2):345-50 - PubMed

Publication Types

Grant support