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Kim J, Kang M, Kim J, et al. A Case of Nocardia farcinica Pneumonia and Mediastinitis in an Immunocompetent Patient. Tuberc Respir Dis (Seoul). 2016;79(2):101-3doi: 10.4046/trd.2016.79.2.101.
Kim, J., Kang, M., Kim, J., Jung, S., Park, J., Lee, D., & Yoon, H. (2016). A Case of Nocardia farcinica Pneumonia and Mediastinitis in an Immunocompetent Patient. Tuberculosis and respiratory diseases, 79(2), 101-3. https://doi.org/10.4046/trd.2016.79.2.101
Kim, Jinyoung, et al. "A Case of Nocardia farcinica Pneumonia and Mediastinitis in an Immunocompetent Patient." Tuberculosis and respiratory diseases vol. 79,2 (2016): 101-3. doi: https://doi.org/10.4046/trd.2016.79.2.101
Kim J, Kang M, Kim J, Jung S, Park J, Lee D, Yoon H. A Case of Nocardia farcinica Pneumonia and Mediastinitis in an Immunocompetent Patient. Tuberc Respir Dis (Seoul). 2016 Apr;79(2):101-3. doi: 10.4046/trd.2016.79.2.101. Epub 2016 Mar 31. PMID: 27066088; PMCID: PMC4823182.
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Tuberc Respir Dis (Seoul). 2016 Apr;79(2):101-3. doi: 10.4046/trd.2016.79.2.101. Epub 2016 Mar 31.

A Case of Nocardia farcinica Pneumonia and Mediastinitis in an Immunocompetent Patient.

Tuberculosis and respiratory diseases

Jinyoung Kim, Minkyu Kang, Juri Kim, Sohee Jung, Junhung Park, Dongkyu Lee, Heejung Yoon

Affiliations

  1. Department of Internal Medicine, Eulji University School of Medicine, Daejeon, Korea.
  2. Department of Infectious Diseases, Seoul Metropolitan Government Seobuk Hospital, Seoul, Korea.

PMID: 27066088 PMCID: PMC4823182 DOI: 10.4046/trd.2016.79.2.101

Abstract

Nocardia species are aerobic, gram-positive pathogens found worldwide in soil. Nocardia is considered an opportunistic pathogen, and its infection mostly occurs in immunocompromised patients. We report a case of Nocardia farcinica induced mediastinitis and pneumonia that occurred in a 64-year-old male patient who had no significant medical history except for hypertension. He visited another hospital with a complaint of dyspnea and left chest wall pain. The symptoms arose 7 days ago without any trauma and they worsened. A mediastinal mass was found on computed tomography scan. After being transferred to our hospital for further evaluation, he was diagnosed with mediastinitis and pneumonia. As N. farcinica was found to be the causative organism by 16S rRNA sequencing, proper antibiotic therapy including trimethoprim/sulfamethoxazole was initiated immediately. After this, the patient improved and he was discharged. If an infection has a disseminating course, nocardiosis cannot be excluded even in immunocompetent patients. Once the diagnosis is established, prompt antibiotic therapy should be performed based on the severity.

Keywords: Nocardia; Pneumonia; Trimethoprim, Sulfamethoxazole Drug Combination

References

  1. Clin Infect Dis. 1994 Mar;18(3):348-53 - PubMed
  2. Thorac Surg Clin. 2012 Aug;22(3):363-74 - PubMed
  3. Clin Microbiol Rev. 1994 Jul;7(3):357-417 - PubMed
  4. Medicine (Baltimore). 2004 Sep;83(5):300-13 - PubMed
  5. J Clin Microbiol. 2003 Oct;41(10):4497-501 - PubMed
  6. Curr Opin Pulm Med. 2006 May;12(3):228-34 - PubMed
  7. Clin Infect Dis. 1996 Jun;22(6):891-903; quiz 904-5 - PubMed
  8. Infection. 2002 Jan;30(1):38-40 - PubMed
  9. Clin Microbiol Rev. 2006 Apr;19(2):259-82 - PubMed
  10. Rev Infect Dis. 1982 Mar-Apr;4(2):315-25 - PubMed
  11. Clin Infect Dis. 2000 Oct;31(4):968-72 - PubMed

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