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Kontogiannis CD, Malliaras K, Kapelios CJ, et al. Continuous internal counterpulsation as a bridge to recovery in acute and chronic heart failure. World J Transplant. 2016;6(1):115-24doi: 10.5500/wjt.v6.i1.115.
Kontogiannis, C. D., Malliaras, K., Kapelios, C. J., Mason, J. W., & Nanas, J. N. (2016). Continuous internal counterpulsation as a bridge to recovery in acute and chronic heart failure. World journal of transplantation, 6(1), 115-24. https://doi.org/10.5500/wjt.v6.i1.115
Kontogiannis, Christos D, et al. "Continuous internal counterpulsation as a bridge to recovery in acute and chronic heart failure." World journal of transplantation vol. 6,1 (2016): 115-24. doi: https://doi.org/10.5500/wjt.v6.i1.115
Kontogiannis CD, Malliaras K, Kapelios CJ, Mason JW, Nanas JN. Continuous internal counterpulsation as a bridge to recovery in acute and chronic heart failure. World J Transplant. 2016 Mar 24;6(1):115-24. doi: 10.5500/wjt.v6.i1.115. PMID: 27011909; PMCID: PMC4801787.
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World J Transplant. 2016 Mar 24;6(1):115-24. doi: 10.5500/wjt.v6.i1.115.

Continuous internal counterpulsation as a bridge to recovery in acute and chronic heart failure.

World journal of transplantation

Christos D Kontogiannis, Konstantinos Malliaras, Chris J Kapelios, Jay W Mason, John N Nanas

Affiliations

  1. Christos D Kontogiannis, Konstantinos Malliaras, Chris J Kapelios, John N Nanas, 3 Department of Cardiology, University of Athens School of Medicine, 11527 Athens, Greece.

PMID: 27011909 PMCID: PMC4801787 DOI: 10.5500/wjt.v6.i1.115

Abstract

Cardiac recovery from cardiogenic shock (CS) and end-stage chronic heart failure (HF) remains an often insurmountable therapeutic challenge. The counterpulsation technique exerts numerous beneficial effects on systemic hemodynamics and left ventricular mechanoenergetics, rendering it attractive for promoting myocardial recovery in both acute and chronic HF. Although a recent clinical trial has questioned the clinical effectiveness of short-term hemodynamic support with intra-aortic balloon pump (IABP, the main representative of the counterpulsation technique) in CS complicating myocardial infarction, the issue remains open to further investigation. Moreover, preliminary data suggest that long-term IABP support in patients with end-stage HF is safe and may mediate recovery of left- or/and right-sided cardiac function, facilitating long-term weaning from mechanical support or enabling the application of other permanent, life-saving solutions. The potential of long-term counterpulsation could possibly be enhanced by implementation of novel, fully implantable counterpulsation devices.

Keywords: Cardiac remodeling; Counterpulsation; Heart failure; Intra-aortic balloon pump; Recovery; Reverse remodeling

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