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Bruning AH, Susi P, Toivola H, et al. Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test. New Microbes New Infect. 2016;11:17-9doi: 10.1016/j.nmni.2016.01.015.
Bruning, A. H., Susi, P., Toivola, H., Christensen, A., Söderlund-Venermo, M., Hedman, K., Aatola, H., Zvirbliene, A., & Koskinen, J. O. (2016). Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test. New microbes and new infections, 1117-9. https://doi.org/10.1016/j.nmni.2016.01.015
Bruning, A H L, et al. "Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test." New microbes and new infections vol. 11 (2016): 17-9. doi: https://doi.org/10.1016/j.nmni.2016.01.015
Bruning AH, Susi P, Toivola H, Christensen A, Söderlund-Venermo M, Hedman K, Aatola H, Zvirbliene A, Koskinen JO. Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test. New Microbes New Infect. 2016 Feb 09;11:17-9. doi: 10.1016/j.nmni.2016.01.015. eCollection 2016 May. PMID: 27014463; PMCID: PMC4789334.
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New Microbes New Infect. 2016 Feb 09;11:17-9. doi: 10.1016/j.nmni.2016.01.015. eCollection 2016 May.

Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test.

New microbes and new infections

A H L Bruning, P Susi, H Toivola, A Christensen, M Söderlund-Venermo, K Hedman, H Aatola, A Zvirbliene, J O Koskinen

Affiliations

  1. Department of Pediatric Infectious Diseases, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
  2. Department of Virology, University of Turku and Biomaterials and Diagnostics Group, Turku University of Applied Sciences, Turku, Finland.
  3. ArcDia International Oy Ltd., Turku, Finland.
  4. Trondheim University Hospital and Norwegian University of Science and Technology, Trondheim, Norway.
  5. Department of Virology, University of Helsinki, and Helsinki University Hospital, Helsinki, Finland.
  6. Department of Immunology and Cell Biology, Institute of Biotechnology, Vilnius University, Lithuania.

PMID: 27014463 PMCID: PMC4789334 DOI: 10.1016/j.nmni.2016.01.015

Abstract

Clinically relevant diagnosis of human bocavirus 1 (HBoV1) is challenging, as the virus is frequently detected in asymptomatic patients, and cofindings with other respiratory viruses are common. The clinical value of current diagnostic methods, such as PCR, is therefore low, and alternative diagnostic strategies are needed. We describe for the first time the use of an antigen detection assay for the rapid identification of HBoV1 in a paediatric patient with respiratory tract infection symptoms. We estimate the duration of active HBoV1 infection to be 6 days.

Keywords: Human bocavirus; human bocavirus 1; point-of-care test; rapid antigen detection assay; respiratory infection

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