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Mansour AM, Haddad RS, Salti HI, et al. Optical Coherence Tomography Findings in Anterior Chamber Ointment Globule after Phacoemulsification. Case Rep Ophthalmol. 2015;6(3):469-76doi: 10.1159/000442970.
Mansour, A. M., Haddad, R. S., Salti, H. I., & Habbal, Z. (2015). Optical Coherence Tomography Findings in Anterior Chamber Ointment Globule after Phacoemulsification. Case reports in ophthalmology, 6(3), 469-76. https://doi.org/10.1159/000442970
Mansour, Ahmad M, et al. "Optical Coherence Tomography Findings in Anterior Chamber Ointment Globule after Phacoemulsification." Case reports in ophthalmology vol. 6,3 (2015): 469-76. doi: https://doi.org/10.1159/000442970
Mansour AM, Haddad RS, Salti HI, Habbal Z. Optical Coherence Tomography Findings in Anterior Chamber Ointment Globule after Phacoemulsification. Case Rep Ophthalmol. 2015 Dec 19;6(3):469-76. doi: 10.1159/000442970. eCollection 2015. PMID: 26955351; PMCID: PMC4777953.
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Case Rep Ophthalmol. 2015 Dec 19;6(3):469-76. doi: 10.1159/000442970. eCollection 2015.

Optical Coherence Tomography Findings in Anterior Chamber Ointment Globule after Phacoemulsification.

Case reports in ophthalmology

Ahmad M Mansour, Randa S Haddad, Haytham I Salti, Zuhair Habbal

Affiliations

  1. Department of Ophthalmology, American University of Beirut, Beirut, Lebanon; Department of Ophthalmology, Rafic Hariri University Hospital, Beirut, Lebanon.
  2. Department of Ophthalmology, American University of Beirut, Beirut, Lebanon.
  3. Department of Pathology and Laboratory Medicine, American University of Beirut, Beirut, Lebanon.

PMID: 26955351 PMCID: PMC4777953 DOI: 10.1159/000442970

Abstract

We present 2 cases of anterior chamber ointment with evidence of progressive endothelial cell loss. In both cases, an anterior segment optical coherence tomography (OCT) was similar to an OCT of a tobramycin-dexamethasone ointment placed on a pen tip. An anterior segment OCT also demonstrated the direct contact of the globule with the corneal endothelium. A gas chromatography/mass spectrometry analysis documented the similarity to tobramycin-dexamethasone ointment in 1 case. Anterior segment OCT can help in confirming the diagnosis. Corneal endothelial injury is a continuous process, and its clinical manifestation is related to the size of the globule, the initial endothelium count, and the duration of ointment contact, which is related to supine positioning. It is advisable to avoid ointments in the immediate postoperative period, especially in corneal wounds larger than 3 mm.

Keywords: Anterior chamber ointment globule; Optical coherence tomography; Phacoemulsification

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