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Clin Transl Gastroenterol. 2016 Mar 17;7:e155. doi: 10.1038/ctg.2016.4.

An Overview of the Diagnosis and Management of Eosinophilic Esophagitis.

Clinical and translational gastroenterology

Manish B Singla, Fouad J Moawad

Affiliations

  1. Gastroenterology Division, Department of Internal Medicine, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.

PMID: 26986655 PMCID: PMC4822098 DOI: 10.1038/ctg.2016.4

Abstract

Eosinophilic esophagitis (EoE) is a chronic inflammatory condition characterized by symptoms of esophageal dysfunction and eosinophilic infiltration of the esophageal mucosa. The diagnosis requires esophageal biopsies demonstrating at least 15 eosinophils per high-powered field following a course of high-dose proton pump inhibitors. Management of EoE consists of the three Ds: drugs, dietary therapy, and esophageal dilation. In this review, we discuss the epidemiology, pathogenesis, diagnosis, and treatment of EoE to include the role of emerging therapies.

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