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Allergo J Int. 2016;25:11-17. doi: 10.1007/s40629-016-0093-5. Epub 2016 Feb 11.

Novel strategies for the treatment of asthma.

Allergo journal international

Marek Lommatzsch, Paul Stoll

Affiliations

  1. Department of Pneumology and Critcal Care Medicine, University of Rostock, Rostock, Germany ; Department of Pneumology and Interdisciplinary, Internal Intensive Care Unit, Medical Clinic I, Center for Internal Medicine, Rostock University Hospital, Ernst-Heydemann-Straße 6, 18057 Rostock, Germany.
  2. Department of Pneumology and Critcal Care Medicine, University of Rostock, Rostock, Germany.

PMID: 27069845 PMCID: PMC4792349 DOI: 10.1007/s40629-016-0093-5

Abstract

Novel treatment strategies are currently emerging for patients with inadequately controlled asthma despite good adherence and trigger avoidance. These strategies serve primarily to reduce or completely avoid long-term oral corticosteroid therapy. A number of these options have already been implemented in practice or will soon be authorized for the treatment of asthma, while others still need to prove their clinical practicability, safety and efficacy. The present article provides an overview of the broad spectrum of novel inhaled, oral, systemic, and invasive treatment strategies for asthma.

Keywords: biologics; inhaled therapy; specific immunotherapy; step-up treatment scheme; thermoplasty

References

  1. Am J Respir Crit Care Med. 2010 Jan 15;181(2):116-24 - PubMed
  2. Respir Med. 2013 Aug;107(8):1141-51 - PubMed
  3. N Engl J Med. 2014 May 29;370(22):2102-10 - PubMed
  4. N Engl J Med. 2014 Sep 25;371(13):1189-97 - PubMed
  5. Clin Exp Allergy. 2014 Aug;44(8):1044-52 - PubMed
  6. Respir Res. 2015 May 17;16:57 - PubMed
  7. Eur Respir J. 2015 Sep;46(3):859-62 - PubMed
  8. Eur Respir J. 2014 Feb;43(2):343-73 - PubMed
  9. Cochrane Database Syst Rev. 2000;(2):CD001186 - PubMed
  10. Dtsch Arztebl Int. 2014 Dec 12;111(50):847-55 - PubMed
  11. Lancet Respir Med. 2015 May;3(5):367-76 - PubMed
  12. N Engl J Med. 2012 Sep 27;367(13):1198-207 - PubMed
  13. Eur Respir J. 2015 May;45(5):1273-82 - PubMed
  14. Am J Respir Crit Care Med. 2014 Dec 15;190(12):1452-4 - PubMed
  15. J Allergy Clin Immunol. 2007 Jan;119(1):254-5; author reply 255 - PubMed
  16. Expert Rev Clin Immunol. 2014 Nov;10(11):1463-74 - PubMed
  17. Lancet. 2012 Aug 18;380(9842):651-9 - PubMed
  18. Thorax. 2013 Apr;68(4):322-9 - PubMed
  19. N Engl J Med. 2011 Sep 22;365(12 ):1088-98 - PubMed
  20. N Engl J Med. 2009 Mar 5;360(10):973-84 - PubMed
  21. Lancet Respir Med. 2014 Nov;2(11):879-90 - PubMed
  22. Thorax. 2015 Jul;70(7):659-67 - PubMed
  23. Clin Exp Allergy. 2014 Nov;44(11):1371-85 - PubMed
  24. Respir Med. 2014 Oct;108(10):1430-7 - PubMed
  25. J Allergy Clin Immunol Pract. 2014 Sep-Oct;2(5):525-36.e1 - PubMed
  26. Thorax. 2013 Jan;68(1):7-8 - PubMed
  27. Semin Respir Crit Care Med. 2012 Dec;33(6):579-87 - PubMed
  28. J Allergy Clin Immunol. 2014 Sep;134(3):568-575.e7 - PubMed
  29. Pneumologie. 2006 Mar;60(3):139-77 - PubMed
  30. N Engl J Med. 2014 Sep 25;371(13):1198-207 - PubMed
  31. J Allergy Clin Immunol. 2015 Sep;136(3):556-68 - PubMed
  32. Chest. 2015 Jun;147(6):1582-90 - PubMed
  33. Ann Am Thorac Soc. 2015 Nov;12(11):1612-8 - PubMed
  34. Lancet Respir Med. 2015 May;3(5):355-66 - PubMed
  35. Thorax. 2014 Jan;69(1):94-6 - PubMed
  36. Lancet Respir Med. 2015 Sep;3(9):692-701 - PubMed
  37. N Engl J Med. 2015 May 21;372(21):1987-95 - PubMed
  38. Allergy. 2005 Mar;60(3):309-16 - PubMed
  39. J Allergy Clin Immunol Pract. 2015 Mar-Apr;3(2):167-74 - PubMed
  40. J Allergy Clin Immunol. 2013 Dec;132(6):1295-302 - PubMed
  41. Lancet. 2000 Dec 23-30;356(9248):2144-8 - PubMed
  42. Allergy. 2013 Jan;68(1):16-26 - PubMed
  43. J Labelled Comp Radiopharm. 2015 May 15;58(5):188-95 - PubMed
  44. N Engl J Med. 2013 Jun 27;368(26):2455-66 - PubMed
  45. Curr Opin Pulm Med. 2014 Jan;20(1):87-94 - PubMed
  46. Allergy. 2006 Jan;61(1):72-8 - PubMed
  47. Allergo J Int. 2014;23(8):282-319 - PubMed
  48. Thorax. 2010 Apr;65(4):370 - PubMed
  49. J Allergy Clin Immunol. 2008 Sep;122(3):507-11.e6 - PubMed
  50. J Allergy Clin Immunol. 2011 Aug;128(2):308-14 - PubMed

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