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Nat Prod Res. 2016 Dec;30(24):2813-2818. doi: 10.1080/14786419.2016.1166494. Epub 2016 Apr 04.

A new antibacterial lupane ester from the seeds of Acokanthera oppositifolia Lam.

Natural product research

Abeer M El Sayed, Shahira M Ezzat, Omar M Sabry

Affiliations

  1. a Pharmacognosy Department , College of Pharmacy, Cairo University , Cairo , Egypt.

PMID: 27046822 DOI: 10.1080/14786419.2016.1166494

Abstract

As a part of ongoing investigation of Acokanthera oppositifolia (Lam.) Codd., four compounds were isolated from its seeds, a new compound; lup-20(29)-en-3β-O-(3'-β-hydroxy) palmitate (1), three known compounds; a triterpene; lupeol (2), a cardiac glycoside; acovenoside A (3) and a sterol; β-sitosterol (4). Their structures were investigated using 1D & 2D-

Keywords: ; Cardenolide; antimicrobial; endocarditis; lupeol ester

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