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ACG Case Rep J. 2016 Jan 20;3(2):115-7. doi: 10.14309/crj.2016.18. eCollection 2016 Jan.

Granular Cell Tumor of the Common Hepatic Duct as an Unusual Cause of Jaundice in a Hepatitis C Patient.

ACG case reports journal

Tripti R Chopade, Colin L Smith, Warren R Maley, Ali A Siddiqui, David A Sass

Affiliations

  1. Division of Gastroenterology and Hepatology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.
  2. Division of Transplant Surgery, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.

PMID: 26958564 PMCID: PMC4748200 DOI: 10.14309/crj.2016.18

Abstract

A 33-year-old woman with a history of intravenous cocaine abuse presented with fatigue, nausea, and jaundice. Serologic testing revealed a positive hepatitis C virus (HCV) antibody and HCV RNA. Ultrasound and magnetic resonance imaging/magnetic resonance cholangiopancreatography showed a partially obstructing lesion in the common hepatic duct, which was confirmed by endoscopic retrograde cholangiopancreatography. Surgical excision revealed a granular cell tumor of the common hepatic duct, with immunohistochemical staining of tumor cells positive for S-100.

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