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Peppas NA, Clegg JR. The challenge to improve the response of biomaterials to the physiological environment. Regen Biomater. 2016;3(2):67-71doi: 10.1093/rb/rbw012.
Peppas, N. A., & Clegg, J. R. (2016). The challenge to improve the response of biomaterials to the physiological environment. Regenerative biomaterials, 3(2), 67-71. https://doi.org/10.1093/rb/rbw012
Peppas, Nicholas A, and Clegg, John R. "The challenge to improve the response of biomaterials to the physiological environment." Regenerative biomaterials vol. 3,2 (2016): 67-71. doi: https://doi.org/10.1093/rb/rbw012
Peppas NA, Clegg JR. The challenge to improve the response of biomaterials to the physiological environment. Regen Biomater. 2016 Jun;3(2):67-71. doi: 10.1093/rb/rbw012. Epub 2016 Mar 10. PMID: 27047671; PMCID: PMC4817319.
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Regen Biomater. 2016 Jun;3(2):67-71. doi: 10.1093/rb/rbw012. Epub 2016 Mar 10.

The challenge to improve the response of biomaterials to the physiological environment.

Regenerative biomaterials

Nicholas A Peppas, John R Clegg

Affiliations

  1. McKetta Department of Chemical Engineering,; Department of Biomedical Engineering,; Institute for Biomaterials, Drug Delivery and Regenerative Medicine; Department of Surgery and Perioperative Care, Dell Medical School and; Division of Pharmaceutics, College of Pharmacy, University of Texas at Austin.
  2. Department of Biomedical Engineering,; Institute for Biomaterials, Drug Delivery and Regenerative Medicine.

PMID: 27047671 PMCID: PMC4817319 DOI: 10.1093/rb/rbw012

Abstract

New applications of biomaterials often require advanced structures containing synthetic and natural components that are tuned to provide properties unique to a specific application. We discuss how structural characteristics of biomaterials, especially hydrophilic ones, can be used in conjunction with non-ideal thermodynamics to develop advanced medical systems. We show a number of examples of biocompatible, intelligent biomaterials that can be used for organ replacement, biosensors, precise drug delivery over days or weeks, and regenerative medicine.

Keywords: drug delivery; materials structure; nanobiomaterials; regenerative mechanism

References

  1. J Control Release. 2002 Oct 4;83(2):223-30 - PubMed
  2. J Am Chem Soc. 2005 Apr 20;127(15):5695-700 - PubMed
  3. J Biomater Sci Polym Ed. 2011;22(11):1523-34 - PubMed
  4. Anal Chim Acta. 2012 Mar 9;718:109-15 - PubMed
  5. Anal Chem. 2011 Mar 15;83(6):2046-55 - PubMed
  6. Macromol Biosci. 2012 Aug;12(8):1137-44 - PubMed
  7. J Biomed Mater Res A. 2008 Jan;84(1):137-47 - PubMed
  8. Anal Chem. 2002 Oct 15;74(20):5161-8 - PubMed
  9. Nature. 1999 Apr 15;398(6728):593-7 - PubMed
  10. J Control Release. 2007 Dec 20;124(3):154-62 - PubMed
  11. Biosens Bioelectron. 2008 Jul 15;23(12):1908-14 - PubMed
  12. Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5157-60 - PubMed
  13. J Biomed Mater Res A. 2006 Jul;78(1):205-10 - PubMed
  14. Acta Biomater. 2012 Feb;8(2):461-73 - PubMed
  15. J Am Chem Soc. 2008 Nov 19;130(46):15242-3 - PubMed

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