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Zarif P, Abdelaal Ahmed Mahmoud A, Abdelhaq MM, et al. Dexmedetomidine versus Magnesium Sulfate as Adjunct during Anesthesia for Laparoscopic Colectomy. Anesthesiol Res Pract. 2016;2016:7172920doi: 10.1155/2016/7172920.
Zarif, P., Abdelaal Ahmed Mahmoud, A., Abdelhaq, M. M., Mikhail, H. M., & Farag, A. (2016). Dexmedetomidine versus Magnesium Sulfate as Adjunct during Anesthesia for Laparoscopic Colectomy. Anesthesiology research and practice, 20167172920. https://doi.org/10.1155/2016/7172920
Zarif, Pierre, et al. "Dexmedetomidine versus Magnesium Sulfate as Adjunct during Anesthesia for Laparoscopic Colectomy." Anesthesiology research and practice vol. 2016 (2016): 7172920. doi: https://doi.org/10.1155/2016/7172920
Zarif P, Abdelaal Ahmed Mahmoud A, Abdelhaq MM, Mikhail HM, Farag A. Dexmedetomidine versus Magnesium Sulfate as Adjunct during Anesthesia for Laparoscopic Colectomy. Anesthesiol Res Pract. 2016;2016:7172920. doi: 10.1155/2016/7172920. Epub 2016 Mar 09. PMID: 27051421; PMCID: PMC4804053.
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Anesthesiol Res Pract. 2016;2016:7172920. doi: 10.1155/2016/7172920. Epub 2016 Mar 09.

Dexmedetomidine versus Magnesium Sulfate as Adjunct during Anesthesia for Laparoscopic Colectomy.

Anesthesiology research and practice

Pierre Zarif, Ahmed Abdelaal Ahmed Mahmoud, Mohamed Mohamed Abdelhaq, Hany M S Mikhail, Ahmed Farag

Affiliations

  1. Department of Anesthesiology, Faculty of Medicine, Cairo University, Giza, Egypt.
  2. Department of Anesthesiology, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt.
  3. Department of General Surgery, Faculty of Medicine, Cairo University, Giza, Egypt.

PMID: 27051421 PMCID: PMC4804053 DOI: 10.1155/2016/7172920

Abstract

Objectives. To compare dexmedetomidine versus magnesium during laparoscopic colectomy. Patients and Methods. 51 patients were randomly allocated into 3 groups: group C (control) received saline infusion, group D dexmedetomidine 1 g/kg and then 0.4 g/kg/hr, and group M MgSO4 2 g and then 15 g/kg/min. Intraoperative hemodynamics were measured before and 1 min after intubation (T1 and T2), before and 5 min after peritoneal insufflation (T3 and T4), before and 5 min after 30° Trendelenburg position (T5 and T6), 5 min after resuming flat position (T7), 5 min after peritoneal deflations (T8), after extubation (T9), and at time of admission to PACU (T10). Recovery time and degree of sedation were assessed. Results. HR and MAP were significantly higher in T2, T4, and T6 compared to T1, T3, and T5, respectively, in all groups with lower measurements in groups D and M compared to group C. Mean of collective measurements was significantly higher in group C. Recovery time and sedation score were significantly higher in groups D and M. Time to Aldrete score of ≥9 was significantly longer in groups D and M. Conclusion. Both drugs ameliorate the pressor responses during LC with a nonsignificant difference. This study is registered with PACTR201602001481308.

References

  1. Br J Anaesth. 2009 Oct;103(4):484-9 - PubMed
  2. Anaesthesist. 2012 Dec;61(12):1059-66 - PubMed
  3. Br J Anaesth. 1999 Nov;83(5):698-701 - PubMed
  4. J Clin Anesth. 2010 Mar;22(2):126-9 - PubMed
  5. Br J Anaesth. 2009 Oct;103(4):561-5 - PubMed
  6. Curr Pharm Des. 2012;18(38):6257-65 - PubMed
  7. Anaesthesia. 2013 Sep;68(9):938-43 - PubMed
  8. J Clin Anesth. 2012 May;24(3):212-20 - PubMed
  9. Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Jul;12 (4):361-3 - PubMed
  10. Indian J Anaesth. 2013 May;57(3):253-8 - PubMed
  11. Rev Assoc Med Bras (1992). 2008 Jul-Aug;54(4):308-13 - PubMed
  12. J Anaesthesiol Clin Pharmacol. 2011 Jul;27(3):344-8 - PubMed
  13. Korean J Anesthesiol. 2013 Jul;65(1):4-8 - PubMed
  14. Br J Anaesth. 2009 Dec;103(6):861-6 - PubMed
  15. Rev Bras Anestesiol. 2012 Jan-Feb;62(1):118-33 - PubMed
  16. Anesthesiology. 2011 Apr;114(4):971-93 - PubMed
  17. Surg Laparosc Endosc Percutan Tech. 2013 Dec;23(6):532-5 - PubMed
  18. Saudi Med J. 2009 Jan;30(1):77-81 - PubMed
  19. Mymensingh Med J. 2013 Jul;22(3):473-7 - PubMed
  20. Sante. 2011 Apr-Jun;21(2):79-81 - PubMed

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