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Ketchum AR, Kappler MP, Wu J, et al. The preparation and characterization of nitric oxide releasing silicone rubber materials impregnated with . J Mater Chem B. 2015;4(3):422-430doi: 10.1039/C5TB01664A.
Ketchum, A. R., Kappler, M. P., Wu, J., Xi, C., & Meyerhoff, M. E. (2016). The preparation and characterization of nitric oxide releasing silicone rubber materials impregnated with . Journal of materials chemistry. B, 4(3), 422-430. https://doi.org/10.1039/C5TB01664A
Ketchum, Alex R, et al. "The preparation and characterization of nitric oxide releasing silicone rubber materials impregnated with ." Journal of materials chemistry. B vol. 4,3 (2016): 422-430. doi: https://doi.org/10.1039/C5TB01664A
Ketchum AR, Kappler MP, Wu J, Xi C, Meyerhoff ME. The preparation and characterization of nitric oxide releasing silicone rubber materials impregnated with . J Mater Chem B. 2016 Jan 21;4(3):422-430. doi: 10.1039/C5TB01664A. Epub 2015 Dec 07. PMID: 27087965; PMCID: PMC4826759.
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J Mater Chem B. 2016 Jan 21;4(3):422-430. doi: 10.1039/C5TB01664A. Epub 2015 Dec 07.

The preparation and characterization of nitric oxide releasing silicone rubber materials impregnated with .

Journal of materials chemistry. B

Alex R Ketchum, Michael P Kappler, Jianfeng Wu, Chuanwu Xi, Mark E Meyerhoff

Affiliations

  1. Department of Chemistry, University of Michigan, Ann Arbor, MI 48109.
  2. Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109.

PMID: 27087965 PMCID: PMC4826759 DOI: 10.1039/C5TB01664A

Abstract

Recently, considerable research efforts have focused on increasing the biocompatibility a nd bactericidal activity of biomedical polymeric devices (e.g., catheters, etc.) through incorporation of nitric oxide (NO) releasing molecules. NO is an important endogenous molecule that is well known for enhancing blood flow via its vasodilatory activity, but it also exhibits potent antithrombotic and antimicrobial properties. In this work, we demonstrate that silicone rubber tubing can be impregnated with a tertiary

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