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Campbell TL, Quadrilatero J. Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin. Data Brief. 2016;7:786-93doi: 10.1016/j.dib.2016.03.009.
Campbell, T. L., & Quadrilatero, J. (2016). Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin. Data in brief, 7786-93. https://doi.org/10.1016/j.dib.2016.03.009
Campbell, Troy L, and Quadrilatero, Joe. "Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin." Data in brief vol. 7 (2016): 786-93. doi: https://doi.org/10.1016/j.dib.2016.03.009
Campbell TL, Quadrilatero J. Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin. Data Brief. 2016 Mar 10;7:786-93. doi: 10.1016/j.dib.2016.03.009. eCollection 2016 Jun. PMID: 27077080; PMCID: PMC4816877.
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Data Brief. 2016 Mar 10;7:786-93. doi: 10.1016/j.dib.2016.03.009. eCollection 2016 Jun.

Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin.

Data in brief

Troy L Campbell, Joe Quadrilatero

Affiliations

  1. Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada.

PMID: 27077080 PMCID: PMC4816877 DOI: 10.1016/j.dib.2016.03.009

Abstract

Skeletal muscle apoptosis and autophagy are catabolic processes that contribute to muscle atrophy during aging, disease, and following muscle injury. In this article, we present data on skeletal muscle apoptosis, autophagy, and morphology in C57BL/6 mice following doxorubicin administration. More specifically, time-course data on caspase-3, caspase-8, caspase-9, calpain, and cathepsin activity are presented, along with data on ATG7, p62, LC3-I, and LC3-II protein expression. Data on skeletal muscle reactive oxygen species (ROS) production, muscle morphology, as well as body and muscle weights are also presented.

Keywords: Apoptosis; Autophagy; Doxorubicin; Skeletal muscle

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