Display options
Cite
Damon DE, Maher YS, Yin M, et al. 2D wax-printed paper substrates with extended solvent supply capabilities allow enhanced ion signal in paper spray ionization. Analyst. 2016;141(12):3866-73doi: 10.1039/c6an00168h.
Damon, D. E., Maher, Y. S., Yin, M., Jjunju, F. P., Young, I. S., Taylor, S., Maher, S., & Badu-Tawiah, A. K. (2016). 2D wax-printed paper substrates with extended solvent supply capabilities allow enhanced ion signal in paper spray ionization. The Analyst, 141(12), 3866-73. https://doi.org/10.1039/c6an00168h
Damon, Deidre E, et al. "2D wax-printed paper substrates with extended solvent supply capabilities allow enhanced ion signal in paper spray ionization." The Analyst vol. 141,12 (2016): 3866-73. doi: https://doi.org/10.1039/c6an00168h
Damon DE, Maher YS, Yin M, Jjunju FP, Young IS, Taylor S, Maher S, Badu-Tawiah AK. 2D wax-printed paper substrates with extended solvent supply capabilities allow enhanced ion signal in paper spray ionization. Analyst. 2016 Jun 21;141(12):3866-73. doi: 10.1039/c6an00168h. Epub 2016 Apr 28. PMID: 27121269.
Copy Download .nbib Format: NLM
Share it on

Analyst. 2016 Jun 21;141(12):3866-73. doi: 10.1039/c6an00168h. Epub 2016 Apr 28.

2D wax-printed paper substrates with extended solvent supply capabilities allow enhanced ion signal in paper spray ionization.

The Analyst

Deidre E Damon, Yosef S Maher, Mengzhen Yin, Fred P M Jjunju, Iain S Young, Stephen Taylor, Simon Maher, Abraham K Badu-Tawiah

Affiliations

  1. Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA. [email protected].

PMID: 27121269 DOI: 10.1039/c6an00168h

Abstract

Paper-based microfluidic channels were created from solid wax printing, and the resultant 2D wax-printed paper substrates were used for paper spray (PS) mass spectrometry (MS) analysis of small organic compounds. Controlling fluid flow at the tip of the wax-printed paper triangles enabled the use of lower spray voltages (0.5-1 kV) and extended signal lifetime (10 minutes) in PS-MS. High sensitivity (sub ng mL(-1) levels) and quantitation precision (<10% RSD) have been achieved in the analysis of illicit drugs in 4 μL of raw urine (fresh and dry), as well as corrosion inhibitors and pesticides in water samples. The reported study encourages the future development of disposable 3D microfluidic paper-based analytical devices, which function with simple operation but capable of on-chip analyte detection by MS; such a device can replace the traditional complex laboratory procedures for MS analysis to enable on-site in situ sampling with portable mass spectrometers.

Publication Types