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Lin YJ, Chien KL, Chen HK, et al. Left Ventricular Dyssynchrony Predicts Left Main Coronary Artery Disease in Patients with Non-ST-Segment Elevation Myocardial Infarction. Acta Cardiol Sin. 2015;31(3):226-31doi: 10.6515/acs20150105a.
Lin, Y. J., Chien, K. L., Chen, H. K., Wang, C. S., & Chu, C. C. (2015). Left Ventricular Dyssynchrony Predicts Left Main Coronary Artery Disease in Patients with Non-ST-Segment Elevation Myocardial Infarction. Acta Cardiologica Sinica, 31(3), 226-31. https://doi.org/10.6515/acs20150105a
Lin, Yueh-Juh, et al. "Left Ventricular Dyssynchrony Predicts Left Main Coronary Artery Disease in Patients with Non-ST-Segment Elevation Myocardial Infarction." Acta Cardiologica Sinica vol. 31,3 (2015): 226-31. doi: https://doi.org/10.6515/acs20150105a
Lin YJ, Chien KL, Chen HK, Wang CS, Chu CC. Left Ventricular Dyssynchrony Predicts Left Main Coronary Artery Disease in Patients with Non-ST-Segment Elevation Myocardial Infarction. Acta Cardiol Sin. 2015 May;31(3):226-31. doi: 10.6515/acs20150105a. PMID: 27122874; PMCID: PMC4805005.
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Acta Cardiol Sin. 2015 May;31(3):226-31. doi: 10.6515/acs20150105a.

Left Ventricular Dyssynchrony Predicts Left Main Coronary Artery Disease in Patients with Non-ST-Segment Elevation Myocardial Infarction.

Acta Cardiologica Sinica

Yueh-Juh Lin, Kuo-Liong Chien, Hsuan-Kuang Chen, Chia-Sung Wang, Ching-Chi Chu

Affiliations

  1. Department of Cardiology, En Chu Kong Hospital;
  2. Institute of Epidemiology and Preventive Medicine, National Taiwan University; ; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

PMID: 27122874 PMCID: PMC4805005 DOI: 10.6515/acs20150105a

Abstract

BACKGROUND: The purpose of our study was to examine whether left ventricular dyssynchrony predicts left main coronary artery stenosis in patients with non-ST-segment elevation myocardial infarction.

METHODS: A total of 100 consecutive patients with non-ST-segment elevation myocardial infarction underwent echocardiography and coronary artery angiography. The 3-dimensional echocardiography-derived left ventricular dyssynchrony parameter was determined by using the standard deviation of the time to the minimal systolic volume for the 16 segments. A stenosis ≥ 50% of the diameter of the left main coronary artery or a stenosis ≥ 70% in 1 or more of the major epicardial vessels or their main branches was considered significant.

RESULTS: The logistic regression analysis revealed that this parameter (odds ratio 1.2; 95% confidence interval, 1.01-1.42; p = 0.04) was the independent predictor of left main coronary artery stenosis. The receiver operating characteristic curve analysis revealed 8.86 as the optimal cutoff value to predict left main coronary artery stenosis (sensitivity, 71.4%; specificity, 89.2%).

CONCLUSIONS: The assessment of left ventricular dyssynchrony by 3-dimensional echocardiography is useful for a noninvasive diagnosis of the left main coronary artery stenosis in patients with non-ST-segment elevation myocardial infarction.

KEY WORDS: Dyssynchrony; Left main coronary artery stenosis; Non-ST-segment elevation myocardial infarction.

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